| Tag | Content |
|---|
| CPLM ID | CPLM-011206 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transmembrane 9 superfamily member 2 |
Protein Synonyms/Alias | |
Gene Name | TMN2 |
Gene Synonyms/Alias | YDR107C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 336 | HSLLRALKSDLARYN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | With EMP70 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 672 AA |
Protein Sequence | MKRGVWLLIY CYATLTKGFS LPGLSPTTYH SGDEIPLLVN RLTPSIYFQH QDEEGNDVSG 60
DKEHFLYSYD YYNKRFHFCR PEHVEKQPES LGSVIFGDRI YNSPFQLNML EEKECVALCK 120
STIPGKDAKF INTLIKSGFF QNWLVDGLPA ARKAYDSRTK TNYYGTGFEL GFTDVKQTVD 180
GKAVPSTMEE LTSEASNEDV ILDARLPKNV KPNLVKTVEL PYFVNHFDIE VEFHDRGNDN 240
YRVVGVIVNP VSIERSSPGA CSTTGKPLIL DEDKDNEVYF TYSVKFVASD TVWATRWDKY 300
LHIYDPQIQW FSLINFSVIV ILLSSVVMHS LLRALKSDLA RYNELNLDNE FHEDSGWKLG 360
HGDVFRTPSK SMLLSILVGS GMQLFLMVMC SIFFAAVGLV SPVSRGSLPT VMFVLYALFG 420
FVGSYASMGV YKFFRGPYWK ANMILTPILL PGAIFLLIVI MNFFLLFAHS SGVIPARSLF 480
FIILLWFLVS VPLSFAGSIV AHKQCNWDEH PTKTNQIARQ IPYQPWYLRT AQATLIAGIF 540
SFGSIAVELY FIYSSLWFNK IFYMFGFLLF SFLLLTLTTS LVTILITYYS LCLENWLWQW 600
RSFIIGGLGC SIYTFIHSIL FTKFKLGGVI TVVLYLGYSL IISALCCVVT GAIGFFSSMF 660
FIRKIYSAIK VE 672 |
Gene Ontology | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD. GO:0016021; C:integral to membrane; ISM:SGD. GO:0006878; P:cellular copper ion homeostasis; IGI:SGD. GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD. GO:0007124; P:pseudohyphal growth; IGI:SGD. GO:0007034; P:vacuolar transport; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |