UniProt Accession

 B1AQP4_HUMAN; B1AQP4 

Genbank Protein ID

 AL591806 

Genbank Nucleotide ID

  

Protein Name

 Nitrilase homolog 1 

Protein Synonyms/Alias

  

Gene Name

 NIT1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
60	QVTSTPDKQQNFKTC	ubiquitination	[1]
108	LSEPLGGKLLEEYTQ	ubiquitination	[1, 2]
141	QDWEQTQKIYNCHVL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 243 AA 

Protein Sequence

Gene Ontology

 GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
 GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro. 

Interpro

 IPR003010; C-N_Hydrolase.
 IPR001110; UPF0012_CS. 

Pfam

 PF00795; CN_hydrolase 

SMART

  

PROSITE

 PS50263; CN_HYDROLASE
 PS01227; UPF0012 

PRINTS