CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030548
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ36765 fis, clone 3NB691000191 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
507VAEVLEGKGAGKKGRubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 543 AA 
Protein Sequence
MARQHARTLW YDRPRYVFME FCVEDSTDVH VLIEDHRIVF SCKNADGVEL YNEIEFYAKV 60
NSKDSQDKRS SRSITCFVRK WKEKVAWPRL TKEDIKPVWL SVDFDNWRDW EGDEEMELAH 120
VEHYAELLKK VSTKRPPPAM DDLDFTTTVV SCCPAELQTE GSNGKKEVLS GFQVVLEDTV 180
LFPEGGGQPD DRGTINDISV LRVTRRGEQA DHFTQTPLDP GSQVLVRVDW ERRFDHMQQH 240
SGQHLITAVA DHLFKLKTTS WELGRFRSAI ELDTPSMTAE QVAAIEQSVN EKIRDRLPVN 300
VRELSLDDPE VEQVSGRGLP DDHAGPIRVV NIEGVDSNMC CGTHVSNLSD LQVIKILGTE 360
KGKKNRTNLI FLSGNRVLKW MERSHGTEKA LTALLKCGAE DHVEAVKKLQ NSTKILQKNN 420
LNLLRDLAVH IAHSLRNSPD WGGVVILHRK EGDSEFMNII ANEIGSEETL LFLTVGDEKG 480
GGLFLLAGPP ASVETLGPRV AEVLEGKGAG KKGRFQGKAT KMSRRMEAQA LLQDYISTQS 540
AKE 543 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004813; F:alanine-tRNA ligase activity; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR018165; Ala-tRNA-synth_IIc_core.
 IPR018164; Ala-tRNA-synth_IIc_N.
 IPR007052; CS-like_domain.
 IPR017447; CS_domain.
 IPR008978; HSP20-like_chaperone.
 IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
 IPR012947; tRNA_SAD. 
Pfam
 PF04969; CS
 PF01411; tRNA-synt_2c
 PF07973; tRNA_SAD 
SMART
 SM00863; tRNA_SAD 
PROSITE
 PS50860; AA_TRNA_LIGASE_II_ALA
 PS51203; CS 
PRINTS