CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020986
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pyrroline-5-carboxylate reductase 3 
Protein Synonyms/Alias
 P5C reductase 3; P5CR 3; Pyrroline-5-carboxylate reductase-like protein 
Gene Name
 Pycrl 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
218QTLLGTAKMLQQEGKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Complete proteome; NADP; Oxidoreductase; Proline biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 274 AA 
Protein Sequence
MAATMSEPRR VGFVGAGRMA EAIARGLIQA GKVEAKQVLA SAPTDNNLCH FRALGCQTTH 60
SNHEVLQNCP LVIFATKPQV LPTVLAEVAP IVTTEHIIVS VAAGISLSTM EGLLPPNTRV 120
LRVSPNLPCV VQEGAMVMAR GHHAGNDDAE LLQNLLEACG QCIEVPESYV DIHTGLSGSG 180
VAFVCTFSEA LAEGAIKMGM PSGLAHRIAA QTLLGTAKML QQEGKHPAQL RTDVLTPAGT 240
TIHGLHALER GGFRAATMSA VEAATCRAKE LSKK 274 
Gene Ontology
 GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
 GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR016040; NAD(P)-bd_dom.
 IPR004455; NADP_OxRdtase_F420.
 IPR000304; Pyrroline-COOH_reductase. 
Pfam
 PF03807; F420_oxidored 
SMART
  
PROSITE
 PS00521; P5CR 
PRINTS