| Tag | Content |
|---|
| CPLM ID | CPLM-023241 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dual specificity protein phosphatase 12 |
Protein Synonyms/Alias | Dual specificity tyrosine phosphatase YVH1 |
Gene Name | DUSP12 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 149 | YEKLQILKPEAKMNE | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 88 160 Tyrosine-protein phosphatase.
ACT_SITE 115 115 Phosphocysteine intermediate (By
MOD_RES 1 1 N-acetylmethionine. |
Keyword | Acetylation; Complete proteome; Hydrolase; Metal-binding; Nucleus; Polymorphism; Protein phosphatase; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 340 AA |
Protein Sequence | MLEAPGPSDG CELSNPSASR VSCAGQMLEV QPGLYFGGAA AVAEPDHLRE AGITAVLTVD 60
SEEPSFKAGP GVEDLWRLFV PALDKPETDL LSHLDRCVAF IGQARAEGRA VLVHCHAGVS 120
RSVAIITAFL MKTDQLPFEK AYEKLQILKP EAKMNEGFEW QLKLYQAMGY EVDTSSAIYK 180
QYRLQKVTEK YPELQNLPQE LFAVDPTTVS QGLKDEVLYK CRKCRRSLFR SSSILDHREG 240
SGPIAFAHKR MTPSSMLTTG RQAQCTSYFI EPVQWMESAL LGVMDGQLLC PKCSAKLGSF 300
NWYGEQCSCG RWITPAFQIH KNRVDEMKIL PVLGSQTGKI 340 |
Gene Ontology | GO:0005737; C:cytoplasm; IBA:RefGenome. GO:0005634; C:nucleus; IDA:HPA. GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. GO:0008270; F:zinc ion binding; TAS:ProtInc. GO:0033133; P:positive regulation of glucokinase activity; IBA:RefGenome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |