UniProt Accession

 IMP4_YEAST; P53941; D6W1A4 

Genbank Protein ID

 X86470; Z71351; BK006947 

Genbank Nucleotide ID

 CAA60184.1; CAA95949.1; DAA10470.1 

Protein Name

 U3 small nucleolar ribonucleoprotein protein IMP4 

Protein Synonyms/Alias

 U3 snoRNP protein IMP4; Interacting with MPP10 protein 4 

Gene Name

 IMP4 

Gene Synonyms/Alias

 YNL075W; N2353 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
28	QDSQLQQKRQIIKQA	ubiquitination	[1]
40	KQALAQGKPLPKELA	ubiquitination	[1]
54	AEDESLQKDFRYDQS	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing. 

Sequence Annotation

 DOMAIN 86 267 Brix.  

Keyword

 Complete proteome; Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; rRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0034457; C:Mpp10 complex; IDA:SGD.
 GO:0032040; C:small-subunit processome; IDA:SGD.
 GO:0042134; F:rRNA primary transcript binding; IPI:SGD.
 GO:0043047; F:single-stranded telomeric DNA binding; IDA:SGD.
 GO:0030515; F:snoRNA binding; IDA:SGD.
 GO:0006364; P:rRNA processing; TAS:SGD. 

Interpro

 IPR004154; Anticodon-bd.
 IPR007109; Brix. 

Pfam

 PF04427; Brix 

SMART

 SM00879; Brix 

PROSITE

 PS50833; BRIX 

PRINTS