CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015833
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein strawberry notch homolog 2 
Protein Synonyms/Alias
  
Gene Name
 Sbno2 
Gene Synonyms/Alias
 Sno; Stno 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
888TESRDLSKYNFENKYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Seems to have transcriptional repression activity in macrophages. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Reference proteome; Repressor; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1349 AA 
Protein Sequence
MLAVEPTMDG DFPPHELPPP GGGIQLQNRL LHCPWWGSFS PSLYPTFSSE NQQFVGSTPF 60
LGGQSCPETS YPTTATVPSF FSKSSDFPQD PSCLEDLSNA SVFSSSVDSL SDIPDTPDFL 120
QADSLNEVPT IWDVSTTSTT HDKLFIPSGP FSAPEDPVTS LSSTPLLISY QSHSQPEEEE 180
GEEEEETEEL GHAETYADYV PSKSKIGKQH PDRVVETSTL SSVPPPDITY TLALPTSDNS 240
TLSALQLEAI TYACQQHEVL LPSGQRAGFL IGDGAGVGKG RTVAGIIVEN YLRGRKKALW 300
FSASNDLKYD AERDLRDIEA PGIAVHALSK IKYGDNTTSE GVLFATYSAL IGESQAGGQH 360
RTRLRQILQW CGEGFDGVIV FDECHKAKNA SSTKMGKAVL DLQSKLPQAR VVYASATGAS 420
EPRNMIYMSR LGIWGEGTPF RTFEEFLHAI EKRGVGAMEI VAMDMKVSGM YIARQLSFSG 480
VTFRIEEIPL SPAFQQVYNR AARLWAEALS VFQQAADWIG LESRKSLWGQ FWSAHQRFFK 540
YLCIAAKVHR LVELAQQELS RDKCVVIGLQ STGEARTREV LDENEGRLDC FVSAAEGVFL 600
SLIQKHFPST RRRRDRGGGK RKRRPRGRGP KASRLSLEAA GVIRISDGSS TESDAGLDSD 660
FNSSPESLVD DDVVIVDAPT HPTDDRGSLY PLQRDLQGPG VVERVERLKQ GLLAKVRALG 720
RELPVNTLDQ LIHQLGGPEC VAEMTGRKGR VVSRPDGTVV FESRAEQGLS IDHVNLREKQ 780
RFMSGEKLVA IISEASSSGV SLQADRRVQN QRRRVHMTLE LPWSADRAIQ QFGRTHRSNQ 840
VSAPEYVFLI SELAGERRFA SIVAKRLESL GALTHGDRRA TESRDLSKYN FENKYGARAL 900
SRVLATIMGQ TDNRVPLPQG YPGGDTAFFR DMKQGLLSVG IGSRESRSGC LDVEKDCSIT 960
KFLNRILGLE VHKQNALFQY FSDTFDHLIE IDKKEGRYDM GILDLAPGIN EIHEESQQVF 1020
LAPGHPQDGQ VVFYKQISVD RGMKWEEALT RSLELKGPYD GFYLSYKVRG SKMSCLLAEQ 1080
NRGEYFTVYK PNIGRQSQLE TLDSLCRKFH RVTVEEAREP WESSYALSLE HCSHTTWNQR 1140
CRLTQEGKCC AQGLRLRHHY MLCGALLRVW GRIAAVMADV SSSSYLQIVR LKTKDKKKQV 1200
GIKIPEGCVH RVLQELQLMD AEVKRRSTHG LAARPPTPRA ITLPCGPGEV LDLTYSPPAE 1260
AFPTPPRFAF PSLPPPDPSS LMLGARDPAT NPVELAHQSC DINFREVLED MLRSLRAGPT 1320
ETPAPLVGVG GGGTERQSVI HFSPPFPNS 1349 
Gene Ontology
 GO:0002281; P:macrophage activation involved in immune response; IMP:UniProtKB.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.
 GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR026937; SBNO_Helicase_C_dom.
 IPR026741; SNO-like. 
Pfam
 PF13871; Helicase_C_4 
SMART
  
PROSITE
  
PRINTS