Tag | Content |
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CPLM ID | CPLM-015833 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein strawberry notch homolog 2 |
Protein Synonyms/Alias | |
Gene Name | Sbno2 |
Gene Synonyms/Alias | Sno; Stno |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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888 | TESRDLSKYNFENKY | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Seems to have transcriptional repression activity in macrophages. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1349 AA |
Protein Sequence | MLAVEPTMDG DFPPHELPPP GGGIQLQNRL LHCPWWGSFS PSLYPTFSSE NQQFVGSTPF 60 LGGQSCPETS YPTTATVPSF FSKSSDFPQD PSCLEDLSNA SVFSSSVDSL SDIPDTPDFL 120 QADSLNEVPT IWDVSTTSTT HDKLFIPSGP FSAPEDPVTS LSSTPLLISY QSHSQPEEEE 180 GEEEEETEEL GHAETYADYV PSKSKIGKQH PDRVVETSTL SSVPPPDITY TLALPTSDNS 240 TLSALQLEAI TYACQQHEVL LPSGQRAGFL IGDGAGVGKG RTVAGIIVEN YLRGRKKALW 300 FSASNDLKYD AERDLRDIEA PGIAVHALSK IKYGDNTTSE GVLFATYSAL IGESQAGGQH 360 RTRLRQILQW CGEGFDGVIV FDECHKAKNA SSTKMGKAVL DLQSKLPQAR VVYASATGAS 420 EPRNMIYMSR LGIWGEGTPF RTFEEFLHAI EKRGVGAMEI VAMDMKVSGM YIARQLSFSG 480 VTFRIEEIPL SPAFQQVYNR AARLWAEALS VFQQAADWIG LESRKSLWGQ FWSAHQRFFK 540 YLCIAAKVHR LVELAQQELS RDKCVVIGLQ STGEARTREV LDENEGRLDC FVSAAEGVFL 600 SLIQKHFPST RRRRDRGGGK RKRRPRGRGP KASRLSLEAA GVIRISDGSS TESDAGLDSD 660 FNSSPESLVD DDVVIVDAPT HPTDDRGSLY PLQRDLQGPG VVERVERLKQ GLLAKVRALG 720 RELPVNTLDQ LIHQLGGPEC VAEMTGRKGR VVSRPDGTVV FESRAEQGLS IDHVNLREKQ 780 RFMSGEKLVA IISEASSSGV SLQADRRVQN QRRRVHMTLE LPWSADRAIQ QFGRTHRSNQ 840 VSAPEYVFLI SELAGERRFA SIVAKRLESL GALTHGDRRA TESRDLSKYN FENKYGARAL 900 SRVLATIMGQ TDNRVPLPQG YPGGDTAFFR DMKQGLLSVG IGSRESRSGC LDVEKDCSIT 960 KFLNRILGLE VHKQNALFQY FSDTFDHLIE IDKKEGRYDM GILDLAPGIN EIHEESQQVF 1020 LAPGHPQDGQ VVFYKQISVD RGMKWEEALT RSLELKGPYD GFYLSYKVRG SKMSCLLAEQ 1080 NRGEYFTVYK PNIGRQSQLE TLDSLCRKFH RVTVEEAREP WESSYALSLE HCSHTTWNQR 1140 CRLTQEGKCC AQGLRLRHHY MLCGALLRVW GRIAAVMADV SSSSYLQIVR LKTKDKKKQV 1200 GIKIPEGCVH RVLQELQLMD AEVKRRSTHG LAARPPTPRA ITLPCGPGEV LDLTYSPPAE 1260 AFPTPPRFAF PSLPPPDPSS LMLGARDPAT NPVELAHQSC DINFREVLED MLRSLRAGPT 1320 ETPAPLVGVG GGGTERQSVI HFSPPFPNS 1349 |
Gene Ontology | GO:0002281; P:macrophage activation involved in immune response; IMP:UniProtKB. GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB. GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |