UniProt Accession

 MEA1_HUMAN; Q16626; Q5TC36; Q9BV01 

Genbank Protein ID

 M27937; L10400; BT009831; AL136304; BC001754 

Genbank Nucleotide ID

 AAA36208.1; AAA36209.1; AAP88833.1; CAI19794.2; AAH01754.1 

Protein Name

 Male-enhanced antigen 1 

Protein Synonyms/Alias

 MEA-1 

Gene Name

 MEA1 

Gene Synonyms/Alias

 MEA 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
173	QWEDVVQKALQARQA	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 May play an important role in spermatogenesis and/or testis development. 

Sequence Annotation

 MOD_RES 114 114 Phosphoserine.  

Keyword

 Complete proteome; Developmental protein; Differentiation; Phosphoprotein; Polymorphism; Reference proteome; Spermatogenesis. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0008584; P:male gonad development; TAS:ProtInc.
 GO:0007283; P:spermatogenesis; TAS:ProtInc. 

Interpro

 IPR009685; MEA1. 

Pfam

 PF06910; MEA1 

SMART

  

PROSITE

  

PRINTS