CPLM-021998

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-021998

UniProt Accession

GPC5C_HUMAN; Q9NQ84; B5BUN4; Q2NL85; Q9NZG5

Genbank Protein ID

AJ276102; AF207989; BT007435; AK131210; AK075397; AB451470; AC079325; CH471099; BC016860; BC110848; BC125080; BC125081

Genbank Nucleotide ID

CAC00633.1; AAF72870.1; AAP36103.1; BAG54752.1; BAC11595.1; BAG70284.1; EAW89163.1; AAH16860.2; AAI10849.1; AAI25081.1; AAI25082.1

Protein Name

G-protein coupled receptor family C group 5 member C

Protein Synonyms/Alias

Retinoic acid-induced gene 3 protein; RAIG-3

Gene Name

GPRC5C

Gene Synonyms/Alias

RAIG3; PSEC0087

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
353	QSMFVENKAFSMDEP	ubiquitination	[1]

Reference

[1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]

Functional Description

This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways (By similarity).

Sequence Annotation

CARBOHYD 191 191 N-linked (GlcNAc...) (Potential).

Keyword

Alternative splicing; Cell membrane; Complete proteome; Cytoplasmic vesicle; G-protein coupled receptor; Glycoprotein; Membrane; Receptor; Reference proteome; Signal; Transducer; Transmembrane; Transmembrane helix.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

441 AA

Protein Sequence

MGTQPEPGLG ARMAIHKALV MCLGLPLFLF PGAWAQGHVP PGCSQGLNPL YYNLCDRSGA 60
WGIVLEAVAG AGIVTTFVLT IILVASLPFV QDTKKRSLLG TQVFFLLGTL GLFCLVFACV 120
VKPDFSTCAS RRFLFGVLFA ICFSCLAAHV FALNFLARKN HGPRGWVIFT VALLLTLVEV 180
IINTEWLIIT LVRGSGEGGP QGNSSAGWAV ASPCAIANMD FVMALIYVML LLLGAFLGAW 240
PALCGRYKRW RKHGVFVLLT TATSVAIWVV WIVMYTYGNK QHNSPTWDDP TLAIALAANA 300
WAFVLFYVIP EVSQVTKSSP EQSYQGDMYP TRGVGYETIL KEQKGQSMFV ENKAFSMDEP 360
VAAKRPVSPY SGYNGQLLTS VYQPTEMALM HKVPSEGAYD IILPRATANS QVMGSANSTL 420
RAEDMYSAQS HQAATPPKDG KNSQVFRNPY VWD 453

Gene Ontology

GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005739; C:mitochondrion; IEA:Compara.
GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.

Interpro

IPR017978; GPCR_3_C.

Pfam

PF00003; 7tm_3

SMART

PROSITE

PS00979; G_PROTEIN_RECEP_F3_1
PS00980; G_PROTEIN_RECEP_F3_2
PS00981; G_PROTEIN_RECEP_F3_3
PS50259; G_PROTEIN_RECEP_F3_4

PRINTS