UniProt Accession

 A2AIU1_MOUSE; A2AIU1 

Genbank Protein ID

 AL732528 

Genbank Nucleotide ID

  

Protein Name

 Interleukin-1 receptor antagonist protein 

Protein Synonyms/Alias

  

Gene Name

 Il1rn 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
17	PSGKRPCKMQAFRIW	acetylation	[1]
29	RIWDTNQKTFYLRNN	acetylation	[1]
79	KLCLSCAKSGDDIKL	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Secreted. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 160 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IDA:MGI.
 GO:0005615; C:extracellular space; IEA:InterPro.
 GO:0031982; C:vesicle; IDA:MGI.
 GO:0030073; P:insulin secretion; IMP:MGI.
 GO:0006629; P:lipid metabolic process; IMP:MGI.
 GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IEA:GOC. 

Interpro

 IPR008996; Cytokine_IL1-like.
 IPR027166; IL-1RA.
 IPR003297; IL-1RA/IL-36.
 IPR020877; Interleukin-1_CS.
 IPR000975; Interleukin_1. 

Pfam

 PF00340; IL1 

SMART

 SM00125; IL1 

PROSITE

 PS00253; INTERLEUKIN_1 

PRINTS

 PR00264; INTERLEUKIN1.
 PR01360; INTRLEUKIN1X.