CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035677
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Staphylococcal nuclease domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Snd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
166FVDSHHQKPVNAIIEacetylation[1]
514VFSGSRLKLYLPKETacetylation[1]
614AERSAYYKPLLSAEEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 881 AA 
Protein Sequence
MVLSGCAIIV RGQPRGGPPP ERQINLSNIR AGNLARRAAA TQPDGKDTPD EPWAFPAREF 60
LRKKLIGKEV CFTIENKTPQ GREYGMIYLG KDTNGENIAE SLVAEGLAPG EGMRANNPEQ 120
NRLSECEEQA KASKKGMWSE GTGHTHPDLK YTIENPRHFV DSHHQKPVNA IIEHVRDGSV 180
VRALLLPDHY LVTVMLSGIK CPTFRRETDG SETPEPFAAE AKFFTESRLL QRDVQIILES 240
CHNQNILGTI LHPNGNITEL LLKEGFARCV DWSIAVYTRG AEKLRAAERF AKERRLRIWR 300
DYVPPTANLD QKDKQFVAKV MQVLNADAIV VKLNSGDYKT IHLSSIRPPR LEGDNIQDKN 360
KKLRPLYDIP YMFEAREFLR KKLIGKKVSV TVDYIRPASP ATETVPAFSE RTCATVTIGG 420
INIAEALVSK GLATVIRYRQ DDDQRSSHYD ELLAAEARAI KNGKGLHSKK EVPIHRVADI 480
SGDTQKAKQF LPFLQRAGRS EAVVEYVFSG SRLKLYLPKE TCLITFLLAG IECPRGARNL 540
PGLVQEGEPF SEEATLFTKE LVLQREVEVE VESMDKAGNF IGWLHMDGAN LSVLLVEHAL 600
SKVHFTAERS AYYKPLLSAE EAAKQRKEKV WAHYEEQPVE EVMPVLEEKE RSASYKPVFV 660
TEITDDLHFY VQDVETGTQL EKLMENMRSD ISSHPPVEGL RPRRGEFCIA KFVDGEWYRA 720
RVEKVESPAK VHVFYIDYGN REILPSTRLG ALPPAFSTRV LPAQATEYAF AFIQVPQDED 780
ARTDAVTVGA DIQNTQCLLN VEHLSASCPH VTLQFADSKG DVGLGLVKEG LVMVEVRKEK 840
QFQKVITEYL NAQESAKSAR LNLWRYGDFR ADDADEFGYS R 881 
Gene Ontology
 GO:0016442; C:RNA-induced silencing complex; IEA:InterPro.
 GO:0004518; F:nuclease activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0031047; P:gene silencing by RNA; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR016685; Silence_cplx_Nase-comp_TudorSN.
 IPR016071; Staphylococal_nuclease_OB-fold.
 IPR006021; Staphylococcal_nuclease.
 IPR002071; Thermonucl_AS.
 IPR002999; Tudor. 
Pfam
 PF00565; SNase
 PF00567; TUDOR 
SMART
 SM00318; SNc
 SM00333; TUDOR 
PROSITE
 PS01284; TNASE_2
 PS50830; TNASE_3
 PS50304; TUDOR 
PRINTS