UniProt Accession

 ATPK_RAT; D3ZAF6 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 ATP synthase subunit f, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Atp5j2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
8	MASIVPLKEKKLMEV	acetylation	[1]
10	SIVPLKEKKLMEVKL	acetylation	[1]
11	IVPLKEKKLMEVKLR	acetylation	[1]
16	EKKLMEVKLRELPSW	acetylation	[1]
48	GYDRYYNKYINVRKG	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; ATP synthesis; CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 88 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IDA:RGD.
 GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.
 GO:0046034; P:ATP metabolic process; IDA:RGD.
 GO:0015992; P:proton transport; IEA:UniProtKB-KW. 

Interpro

 IPR019344; F1F0-ATPsyn_F_prd. 

Pfam

 PF10206; WRW 

SMART

  

PROSITE

  

PRINTS