CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026220
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myosin phosphatase Rho-interacting protein 
Protein Synonyms/Alias
  
Gene Name
 Mprip 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
359FKKGWLTKQYEDGQWubiquitination[1]
1057TEIKLQEKEECLRRFacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2269 AA 
Protein Sequence
MSAAKENPCR KFQANIFNKS KCQNCFKPRE SHLLNDEDLT QAKPIYGGWL LLAPDGTDFD 60
NPVHRSRKWQ RRFFILYEHG LLRYALDEMP TTLPQGTINM NQCTDVVDGE ARTGQKFSLC 120
ILTPDKEHFI RAETKEIISG WLEMLMVYPR TNKQNQKKKR KVEPPTPQEP GPAKMAVTSS 180
SGGSSGSSSS IPSAEKVPTT KSTLWQEEMR AKDQPDGTSL SPAQSPSQSQ PPAACTPREP 240
GLESKEDEST ISGDRVDGGR KVRVESGYFS LEKAKQDLRA EEQLPPLLSP PSPSTPHSRR 300
SQVIEKFEAL DIEKAEHMET NMLILTTPSS DTRQGRSERR AIPRKRPDLL NFKKGWLTKQ 360
YEDGQWKKHW FVLADQSLRY YRDSVAEEAA DLDGEINLST CYDVTEYPVQ RNYGFQIHTK 420
EGEFTLSAMT SGIRRNWIQT IMKHVLPASA PDVTSSLPEG KNKSTSFETC SRSTEKQEAE 480
PGEPDPEQKK SRARERRREG RSKTFDWAEF RPIQQALAQE RASAVGSSDS GDPGCLEAEP 540
GELERERARR REERRKRFGM LDTIDGPGME DTALRMDIDR SPGLLGTPDL KTQNVHVEIE 600
QRWHQVETTP LREEKQVPIA PLHLSLEDRS ERLSTHELTS LLEKELEQSQ KEASDLLEQN 660
RLLQDQLRVA LGREQSAREG YVLQTEVATS PSGAWQRLHR VNQDLQSELE AQCRRQELIT 720
QQIQTLKHSY GEAKDAIRHH EAEIQTLQTR LGNAAAELAI KEQALAKLKG ELKMEQGKVR 780
EQLEEWQHSK AMLSGQLRAS EQKLRSTEAR LLEKTQELRD LETQQALQRD RQKEVQRLQE 840
CIAELSQQLG TSEQAQRLME KKLKRNYTLL LESCEQEKQA LLQNLKEVED KASAYEDQLQ 900
GHVQQVEALQ KEKLSETCKG SEQVHKLEEE LEAREASIRQ LAQHVQSLHD ERDLIKHQFQ 960
ELMERVATSD GDVAELQEKL RGKEVDYQNL EHSHHRVSVQ LQSVRTLLRE KEEELKHIKE 1020
THERVLEKKD QDLNEALVKM IALGSSLEET EIKLQEKEEC LRRFVSDSPK DAKEPLSTTE 1080
PTEEGSGILP LGSVTRVFPG FPHSQPEDED PSAGLGEEGS SGSLSREENT ILPKSADMPE 1140
REGHLQSTSK SDPGAPIKRP RIRFSTIQCQ RYIHPEGCAK AWTSSTSSDT SQDQSPSEDS 1200
VSSEATPNTL PAAADAETYI SIIHSLETKL YVTEEKLKDV TVRLESQQGQ SQEALLALHQ 1260
QWAGTEAQLR EQLRASLLQA SALASQLEQE RQQKATNIEH HPGELEDFQA KNSQALTCLE 1320
NCWKKLRSLP WADQEEGQDA CAASLANIES MLVSAIKALQ PWASPAESRT QAEQEKEHPI 1380
ESGMAAPVQQ PCQPILNEQE HRKLLSAQIV LEASLINQIA DSLKNTTSDV YGVLCELTQS 1440
GEWPLKEESA APSAGAPVEI WAKKVLVNGE FWSQVESLSK HLGTLGEETA CTSGDRQQHT 1500
PQSLADATWI RAELSYATQS VRELFHHRLQ SIQETLQGTQ AALQQHKCML GEILGAYQTP 1560
DFERVIQQIL ETLRHPTGRE DQVQTSWDQN PLGEILRPGT DGSQEPLQAL HQSPEVLAAI 1620
QDELAQQLRE KASILEEISA ALPVLPPTEP LGGCQRLLRM SQHLSYESCL EGLGQYSSLL 1680
VQDAIIQAQV CYAACRIRLE YEKELRFYKK ACQEAKGASG QKRAQAVGAL KEEYEELLHK 1740
QKSEYQKVIT LIEKENTELK AKVSQMDHQQ RCLQEAENKH SESMFALQGR YEEEIRCMVE 1800
QLSHTENTLQ AERSRVLSQL DASVKDRQAM EQHHVQQMKM LEDRFQLKVR ELQAVHQEEL 1860
RALQEHYIWS LRGALSLYQP SHPDSSLAPG PSEPRAVPAA KDEAESMSGL RERIQELEAQ 1920
MGVMREELGH KELEGDVAAL QEKYQRDFES LKATCERGFA AMEETHQKKI EDLQRQHQRE 1980
LEKLREEKDR LLAEETAATI SAIEAMKNAH REEMERELEK SQRSQISSIN SDIEALRRQY 2040
LEELQSVQRE LEVLSEQYSQ KCLENAHLAQ ALEAERQALR QCQRENQELN AHNQELNNRL 2100
AAEITRLRTL LTGDGGGEST GLPLTQGKDA YELEVLLRVK ESEIQYLKQE ISSLKDELQT 2160
ALRDKKYASD KYKDIYTELS IAKAKADCDI SRLKEQLKAA TEALGEKSPE GTTVSGYDIM 2220
KSKSNPDFLK KDRSCVTRQL RNIRSKSLKE GLTVQERLKL FESRDLKKD 2269 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS