CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028423
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 40S ribosomal protein S6 
Protein Synonyms/Alias
  
Gene Name
 RPS6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
14FPATGCQKLIEVDDEacetylation[1, 2]
14FPATGCQKLIEVDDEubiquitination[2, 3, 4]
30KLRTFYEKRMATEVAubiquitination[4]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 91 AA 
Protein Sequence
MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKVKVD KLLQVFKSET 60
VNAIGNWYLE WGSDSGFWLL TFGKLLPNAT L 91 
Gene Ontology
 GO:0005840; C:ribosome; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR001377; Ribosomal_S6e. 
Pfam
 PF01092; Ribosomal_S6e 
SMART
  
PROSITE
  
PRINTS