UniProt Accession

 H0YCG7_HUMAN; H0YCG7 

Genbank Protein ID

 AC114491; AL353892; AL391235; AL513206; AL591042 

Genbank Nucleotide ID

  

Protein Name

 Guanine nucleotide exchange factor VAV3 

Protein Synonyms/Alias

  

Gene Name

 VAV3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
80	FTRVTSCKVCQMLLR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 

Interpro

 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 

Pfam

 PF00130; C1_1
 PF07653; SH3_2 

SMART

 SM00109; C1
 SM00326; SH3 

PROSITE

 PS50003; PH_DOMAIN
 PS50002; SH3
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 

PRINTS