CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022797
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UDP-glucuronic acid decarboxylase 5 
Protein Synonyms/Alias
 UDP-XYL synthase 5; UDP-glucuronate decarboxylase 5; UGD; UXS-5 
Gene Name
 UXS5 
Gene Synonyms/Alias
 At3g46440; F18L15.160 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
6**MASSDKQTSPKPPacetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031
Functional Description
 Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity). 
Sequence Annotation
 NP_BIND 60 85 NAD (By similarity).
 NP_BIND 172 176 NAD (By similarity).
 NP_BIND 214 218 Substrate (By similarity).
 NP_BIND 231 238 Substrate (By similarity).
 NP_BIND 298 302 Substrate (By similarity).
 ACT_SITE 172 172 Proton acceptor (By similarity).
 BINDING 169 169 Substrate (By similarity).
 BINDING 201 201 Substrate (By similarity).
 BINDING 213 213 NAD (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Decarboxylase; Lyase; NAD; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 341 AA 
Protein Sequence
MASSDKQTSP KPPPSPSPLR NSKFCQSNMR ILISGGAGFI GSHLVDKLME NEKNEVIVAD 60
NYFTGSKDNL KKWIGHPRFE LIRHDVTEPL LIEVDQIYHL ACPASPIFYK YNPVKTIKTN 120
VIGTLNMLGL AKRVGARILL TSTSEVYGDP LIHPQPESYW GNVNPIGVRS CYDEGKRVAE 180
TLMFDYHRQH GIEIRIARIF NTYGPRMNID DGRVVSNFIA QALRGEALTV QKPGTQTRSF 240
CYVSDMVDGL MRLMEGDDTG PINIGNPGEF TMVELAETVK ELINPSIEIK MVENTPDDPR 300
QRKPDITKAK EVLGWEPKVK LREGLPLMEE DFRLRLGVHK N 341 
Gene Ontology
 GO:0005829; C:cytosol; IDA:TAIR.
 GO:0050662; F:coenzyme binding; IEA:InterPro.
 GO:0048040; F:UDP-glucuronate decarboxylase activity; IEA:EC.
 GO:0042732; P:D-xylose metabolic process; TAS:TAIR.
 GO:0033320; P:UDP-D-xylose biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR001509; Epimerase_deHydtase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01370; Epimerase 
SMART
  
PROSITE
  
PRINTS