CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019637
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 347 
Protein Synonyms/Alias
 Zinc finger protein 1111 
Gene Name
 ZNF347 
Gene Synonyms/Alias
 ZNF1111 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
240HISKKYLKDFISSLLacetylation[1]
253LLLTQGQKANNWGSPacetylation[1]
346HTGEKPYKCNECGKVubiquitination[2]
371RGIHTGEKPYKCNECubiquitination[2]
763RGIHTGEKPYKCNECubiquitination[2]
766HTGEKPYKCNECGKAubiquitination[2]
772YKCNECGKAFSQTSKubiquitination[2]
Reference
 [1] Monoclonal antibody cocktail as an enrichment tool for acetylome analysis.
 Shaw PG, Chaerkady R, Zhang Z, Davidson NE, Pandey A.
 Anal Chem. 2011 May 15;83(10):3623-6. [PMID: 21466224]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 8 79 KRAB.
 ZN_FING 261 283 C2H2-type 1; degenerate.
 ZN_FING 289 311 C2H2-type 2.
 ZN_FING 317 339 C2H2-type 3.
 ZN_FING 345 367 C2H2-type 4.
 ZN_FING 373 395 C2H2-type 5.
 ZN_FING 401 423 C2H2-type 6.
 ZN_FING 429 451 C2H2-type 7.
 ZN_FING 457 479 C2H2-type 8.
 ZN_FING 485 507 C2H2-type 9.
 ZN_FING 513 535 C2H2-type 10.
 ZN_FING 541 563 C2H2-type 11.
 ZN_FING 569 591 C2H2-type 12.
 ZN_FING 597 619 C2H2-type 13.
 ZN_FING 625 647 C2H2-type 14; degenerate.
 ZN_FING 653 675 C2H2-type 15.
 ZN_FING 681 703 C2H2-type 16.
 ZN_FING 709 731 C2H2-type 17.
 ZN_FING 737 759 C2H2-type 18.
 ZN_FING 765 787 C2H2-type 19.
 ZN_FING 790 812 C2H2-type 20; degenerate.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 839 AA 
Protein Sequence
MALTQGQVTF RDVAIEFSQE EWTCLDPAQR TLYRDVMLEN YRNLASLGIS CFDLSIISML 60
EQGKEPFTLE SQVQIAGNPD GWEWIKAVIT ALSSEFVMKD LLHKGKSNTG EVFQTVMLER 120
QESQDIEGCS FREVQKNTHG LEYQCRDAEG NYKGVLLTQE GNLTHGRDEH DKRDARNKLI 180
KNQLGLSLQS HLPELQLFQY EGKIYECNQV EKSFNNNSSV SPPQQMPYNV KTHISKKYLK 240
DFISSLLLTQ GQKANNWGSP YKSNGCGMVF PQNSHLASHQ RSHTKEKPYK CYECGKAFRT 300
RSNLTTHQVI HTGEKRYKCN ECGKVFSRNS QLSQHQKIHT GEKPYKCNEC GKVFTQNSHL 360
VRHRGIHTGE KPYKCNECGK AFRARSSLAI HQATHSGEKP YKCNECGKVF TQNSHLTNHW 420
RIHTGEKPYK CNECGKAFGV RSSLAIHLVI HTGEKPYKCH ECGKVFRRNS HLARHQLIHT 480
GEKPYKCNEC GKAFRAHSNL TTHQVIHTGE KPYKCNECGK VFTQNSHLAN HQRIHTGVKP 540
YMCNECGKAF SVYSSLTTHQ VIHTGEKPYK CNECGKVFTQ NSHLARHRGI HTGEKPYKCN 600
ECGKVFRHNS YLSRHQRIHT GEKPYKYNEY GKAFSEHSNL TTHQVIHTGE KPYKCNECGK 660
VFTQNSHLAR HRRVHTGGKP YQCNECGKAF SQTSKLARHQ RVHTGEKPYE CNQCGKAFSV 720
RSSLTTHQAI HTGKKPYKCN ECGKVFTQNS HLARHRGIHT GEKPYKCNEC GKAFSQTSKL 780
ARHQRIHTGE KPYECGKPFS ICSSLTTHQT IHTGGKPYKC NVWKVLKSEF KPCKPSQNS 839 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS