CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020659
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alpha-hemoglobin-stabilizing protein 
Protein Synonyms/Alias
 Erythroid differentiation-related factor; Erythroid-associated factor 
Gene Name
 Ahsp 
Gene Synonyms/Alias
 Edrf; Eraf 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
54LYTNYYKKLVHGEQEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. 
Sequence Annotation
  
Keyword
 Chaperone; Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 102 AA 
Protein Sequence
MAPFQSNKDL ISTGIKEFNV LLDQQVFDDP LISEEDMVIV VHDWVNLYTN YYKKLVHGEQ 60
EEQDRAMTEF QQELSTLGSQ FLAKYRTFLK SKEPPSNTLP SS 102 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0030218; P:erythrocyte differentiation; IMP:MGI.
 GO:0020027; P:hemoglobin metabolic process; IEA:InterPro.
 GO:0006457; P:protein folding; IDA:MGI.
 GO:0050821; P:protein stabilization; IDA:MGI. 
Interpro
 IPR015317; A_Hb_stabilising_prot. 
Pfam
 PF09236; AHSP 
SMART
  
PROSITE
  
PRINTS