CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032319
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat and FYVE domain containing 1 
Protein Synonyms/Alias
  
Gene Name
 Ankfy1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
279ATTLVSHKADVDMVDubiquitination[1]
636AIQRQDSKSALFLLEubiquitination[1]
851AMTYKNNKAAEAILKubiquitination[1]
858KAAEAILKRESGAAEubiquitination[1]
931NLLLAGAKVNELTKHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Metal-binding; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1169 AA 
Protein Sequence
MAEEEVAKLE KHLMLLRQEY VKLQKKLAET EKRCTLLAAQ ANKENSNESF ISRLLAIVAG 60
LYEQEQYSDL KIKVGDRHIS AHKFVLAARS DSWSLANLSS TEEIDLSDAN PEVTMTMLRW 120
IYTDELEFRE DDVFLTELMK LANRFQLQLL RERCEKGVMS LVNVRNCIRF YQTAEELNAS 180
TLMNYCAEII ASHWDDLRKE DFSSLSAQLL YKMIKSKTEY PLHKAIKVER EDVVFLYLIE 240
MDSQLPGKLN ETDHNGDLAL DLALSRRLES IATTLVSHKA DVDMVDKNGW SLLHKGIQRG 300
DLFASTFLIK NGALVNAATA GAQETPLHLV ALYSPKKYSA DVMSEMAQIA EALLQAGANP 360
NMQDSKGRTP LHLSIMARND CVFSQLLQCK QLDLELKDHE GSTALWLAVQ YITVSSDQSV 420
NPFEDLPVVN GTSFDENSFA ARLIQRGSNT DAPDVMTGNC LLQRAAGAGN EAAALFLATS 480
GAHANHRNKW GETPLHTACR HGLANLTAEL LQQGANPNLQ TEEALPVPKE SPVLMSSADG 540
IYLQTPLHMA IAYNHPDVVS VILEQKANAL HATNNLQIIP DFSLKDSRDQ TVLGLALWTG 600
MHTIAAQLLG SGASINDTMS DGQTLLHMAI QRQDSKSALF LLEHQADINV RTQDGETALQ 660
LAIKHQLPLV VDAICTRGAD MSVPDEKGNP PLWLALASNL EDIASTLVRH GCDATCWGPG 720
PSGCLQTLLH RAIDENNEST ACFLIRSGCD VNSPRQPGTN GEGEEEARDG QTPLHLAASW 780
GLEETVQCLL EFGANVNAQD AEGRTPVHVA ISNQHSVIIQ LLISHPNIEL SVRDRQGLTP 840
FACAMTYKNN KAAEAILKRE SGAAEQVDNK GRNFLHVAVQ NSDIESVLFL ISVQANVNSR 900
VQDASKLTPL HLAVQAGSEI IVRNLLLAGA KVNELTKHRQ TALHLAAQQD LPTICSVLLE 960
NGVDFAAVDE NGNNALHLAV MHGRLNNIRA LLTECTVDAE AFNLRGQSPL HILGQYGKEN 1020
AAAIFDLFLE CMPEYPLDKP DAEGNTVLLL AYMKGNANLC RAIVRSGVRL GVNNNQGVNI 1080
FNYQVATKQL LFRLLDMLSK EPPWCDGSNC YECTAKFGVT TRKHHCRHCG RLLCHKCSTK 1140
EIPIIKFDLN KPVRVCNICF DVLTLGGVS 1169 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR000306; Znf_FYVE.
 IPR017455; Znf_FYVE-rel.
 IPR011011; Znf_FYVE_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF12796; Ank_2
 PF00651; BTB
 PF01363; FYVE 
SMART
 SM00248; ANK
 SM00225; BTB
 SM00064; FYVE 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50097; BTB
 PS50178; ZF_FYVE 
PRINTS
 PR01415; ANKYRIN.