UniProt Accession

 F5H4V2_HUMAN; F5H4V2 

Genbank Protein ID

 AC122688 

Genbank Nucleotide ID

  

Protein Name

 Acetoacetyl-CoA synthetase 

Protein Synonyms/Alias

  

Gene Name

 AACS 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
59	EKLQQVVKGLPDLKK	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 98 AA 

Protein Sequence

Gene Ontology

 GO:0047760; F:butyrate-CoA ligase activity; IEA:Compara.
 GO:0060612; P:adipose tissue development; IEA:Compara.
 GO:0071397; P:cellular response to cholesterol; IEA:Compara.
 GO:0071333; P:cellular response to glucose stimulus; IEA:Compara.
 GO:0071394; P:cellular response to testosterone stimulus; IEA:Compara.
 GO:0001889; P:liver development; IEA:Compara.
 GO:0032024; P:positive regulation of insulin secretion; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara.
 GO:0034201; P:response to oleic acid; IEA:Compara.
 GO:0014074; P:response to purine-containing compound; IEA:Compara.
 GO:0042594; P:response to starvation; IEA:Compara.
 GO:0050872; P:white fat cell differentiation; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS