CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003566
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional regulatory protein YehT 
Protein Synonyms/Alias
  
Gene Name
 yehT 
Gene Synonyms/Alias
 b2125; JW5352 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
110IDEARLEKTLARLRQacetylation[1]
121RLRQERSKQDVSLLPacetylation[1]
135PENQQALKFIPCTGHacetylation[1]
234RRYLKSLKEAIGL**acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Member of the two-component regulatory system YehU/YehT, which may be involved in the stationary-phase control network. Regulates expression of yjiY by binding to its promoter region. 
Sequence Annotation
 DOMAIN 3 116 Response regulatory.
 DOMAIN 137 239 HTH LytTR-type.
 MOD_RES 54 54 4-aspartylphosphate (By similarity).  
Keyword
 Complete proteome; DNA-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 239 AA 
Protein Sequence
MIKVLIVDDE PLARENLRVF LQEQSDIEIV GECSNAVEGI GAVHKLRPDV LFLDIQMPRI 60
SGLEMVGMLD PEHRPYIVFL TAFDEYAIKA FEEHAFDYLL KPIDEARLEK TLARLRQERS 120
KQDVSLLPEN QQALKFIPCT GHSRIYLLQM KDVAFVSSRM SGVYVTSHEG KEGFTELTLR 180
TLESRTPLLR CHRQYLVNLA HLQEIRLEDN GQAELILRNG LTVPVSRRYL KSLKEAIGL 239 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0000160; P:phosphorelay signal transduction system; IDA:EcoCyc.
 GO:0006355; P:regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR011006; CheY-like_superfamily.
 IPR007492; LytTR_DNA-bd_dom.
 IPR001789; Sig_transdc_resp-reg_receiver. 
Pfam
 PF04397; LytTR
 PF00072; Response_reg 
SMART
 SM00850; LytTR
 SM00448; REC 
PROSITE
 PS50930; HTH_LYTTR
 PS50110; RESPONSE_REGULATORY 
PRINTS