UniProt Accession

 C9JTV5_HUMAN; C9JTV5 

Genbank Protein ID

 AC021016; AC097483 

Genbank Nucleotide ID

  

Protein Name

 Actin-related protein 2/3 complex subunit 2 

Protein Synonyms/Alias

  

Gene Name

 ARPC2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
65	SISLKFYKELQAHGA	ubiquitination	[1, 2]
77	HGADELLKRVYGSFL	acetylation	[3]
77	HGADELLKRVYGSFL	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 90 AA 

Protein Sequence

Gene Ontology

 GO:0031252; C:cell leading edge; IEA:Compara.
 GO:0005856; C:cytoskeleton; IEA:InterPro.
 GO:0005768; C:endosome; IEA:Compara.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0030838; P:positive regulation of actin filament polymerization; IEA:Compara.
 GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IEA:Compara. 

Interpro

 IPR007188; P34-arc. 

Pfam

  

SMART

  

PROSITE

  

PRINTS