CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033766
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar GTP-binding protein 1 
Protein Synonyms/Alias
  
Gene Name
 GTPBP4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
103LGQINIAKNLVDNVAubiquitination[1]
118KDYVRLMKYGDSLYRubiquitination[1]
145CTVIKRQKQSLEYLEubiquitination[1]
203QPYAFTTKSLFVGHMubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Involved in the biogenesis of the 60S ribosomal subunit (By similarity). 
Sequence Annotation
  
Keyword
 GTP-binding; Nucleotide-binding; Nucleus; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 634 AA 
Protein Sequence
MAHYNFKKIT VVPSAKDFID LTLSKTQRKT PTVIHKHYQI HRIRHFYMRK VKFTQQNYHD 60
RLSQILTDFP KLDDIHPFYA DLMNILYDKD HYKLALGQIN IAKNLVDNVA KDYVRLMKYG 120
DSLYRCKQLK RAALGRMCTV IKRQKQSLEY LEQVRQHLSR LPTIDPNTRT LLLCGYPNVG 180
KSSFINKVTR ADVDVQPYAF TTKSLFVGHM DYKYLRWQVV DTPGILDHPL EDRNTIEMQA 240
ITALAHLRAA VLYVMDLSEQ CGHGLREQLE LFQNIRPLFI NKPLIVVANK CDVKRIAELS 300
EDDQKIFTDL QSEGFPVIET STLTEEGVIK VKTEACDRLL AHRVETKMKG NKVNEVLNRL 360
HLAIPTRRDD KERPPFIPEG VVARRKRMET EESRKKRERD LELEMGDDYI LDLQKYWDLM 420
NLSEKHDKIP EIWEGHNIAD YIDPAIMKKL EELEKEEELR TAAGEYDSVS ESEDEEMLEI 480
RQLAKQIREK KKLKILESKE KNTQGPRMPR TAKKVQRTVL EKEMRSLGVD MDDKDDAHYA 540
VQARRSRSIT RKRKREDSAP PSSVARSGSC SRTPRDVSGL RDVKMVKKAK TMMKNAQKKM 600
NRLGKKGEAD RHVFDMKPKH LLSGKRKAGK KDRR 634 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR006073; GTP_binding_domain.
 IPR024926; NOG1.
 IPR010674; NOG1_Rossman_fold_dom.
 IPR012973; NOG_C.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom. 
Pfam
 PF06858; NOG1
 PF08155; NOGCT 
SMART
  
PROSITE
  
PRINTS
 PR00326; GTP1OBG.