CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-040350
UniProt Accession
F6YFW9_MOUSE
;
F6YFW9
Genbank Protein ID
AC105947
;
AC140316
Genbank Nucleotide ID
Protein Name
E3 ubiquitin-protein ligase MIB1
Protein Synonyms/Alias
Gene Name
Mib1
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
195
GNIPVLQ
K
DKDNTNV
ubiquitination
[1]
208
NVNADVQ
K
LQQQLQD
ubiquitination
[1]
Reference
[1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [
PMID: 22790023
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
265 AA
Protein Sequence
XGTQGAEKKS AASIACFLAA NGADLSIRNK KGQSPLDLCP DPSLCKALAK CHKEKVSGQV 60
GSRSPSMISN DSETLEECMV CSDMKRDTLF GPCGHIATCS LCSPRVKKCL ICKEQVQSRT 120
KIEECVVCSD KKAAVLFQPC GHMCACENCA SLMKKCVQCR AVVERRVPFI TCCGGKSSED 180
PSDEISSGNI PVLQKDKDNT NVNADVQKLQ QQLQDIKEQT MCPVCLDRLK NMIFLCGHGT 240
CQLCGDRMSE CPICRKAIER RILLY 265
Gene Ontology
GO:0031410
; C:cytoplasmic vesicle; IDA:MGI.
GO:0008270
; F:zinc ion binding; IEA:InterPro.
GO:0001568
; P:blood vessel development; IMP:MGI.
GO:0001947
; P:heart looping; IMP:MGI.
GO:0001701
; P:in utero embryonic development; IMP:MGI.
GO:0045665
; P:negative regulation of neuron differentiation; IMP:MGI.
GO:0001841
; P:neural tube formation; IMP:MGI.
GO:0007219
; P:Notch signaling pathway; IMP:MGI.
GO:0045807
; P:positive regulation of endocytosis; IDA:MGI.
GO:0001756
; P:somitogenesis; IMP:MGI.
Interpro
IPR001841
; Znf_RING.
IPR013083
; Znf_RING/FYVE/PHD.
Pfam
SMART
SM00184
; RING
PROSITE
PS50089
; ZF_RING_2
PRINTS