UniProt Accession

 D3Z7R6_MOUSE; D3Z7R6 

Genbank Protein ID

 AC151846 

Genbank Nucleotide ID

  

Protein Name

 Calponin-2 

Protein Synonyms/Alias

  

Gene Name

 Cnn2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
8	MSSTQFNKGPSYGLS	acetylation	[1, 2]
25	VKNRLLSKYDPQKEA	acetylation	[1]
30	LSKYDPQKEAELRSW	acetylation	[1]
52	SIGPDFQKGLKDGVI	acetylation	[1]
55	PDFQKGLKDGVILCT	acetylation	[1]
195	RRHIYDTKLGTDKCD	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 266 AA 

Protein Sequence

Gene Ontology

 GO:0001725; C:stress fiber; ISO:MGI.
 GO:0031032; P:actomyosin structure organization; IEA:InterPro.
 GO:0071260; P:cellular response to mechanical stimulus; ISO:MGI.
 GO:0030097; P:hemopoiesis; IMP:MGI.
 GO:0030336; P:negative regulation of cell migration; IMP:MGI.
 GO:0050765; P:negative regulation of phagocytosis; IMP:MGI.
 GO:0010628; P:positive regulation of gene expression; IMP:MGI.
 GO:0032970; P:regulation of actin filament-based process; ISO:MGI.
 GO:0042127; P:regulation of cell proliferation; IMP:MGI.
 GO:0042060; P:wound healing; IMP:MGI. 

Interpro

 IPR001997; Calponin.
 IPR000557; Calponin_repeat.
 IPR001715; CH-domain.
 IPR003096; SM22_calponin. 

Pfam

 PF00402; Calponin
 PF00307; CH 

SMART

 SM00033; CH 

PROSITE

 PS01052; CALPONIN_1
 PS51122; CALPONIN_2
 PS50021; CH 

PRINTS

 PR00889; CALPONIN.
 PR00888; SM22CALPONIN.