CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044676
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Troponin T, cardiac muscle 
Protein Synonyms/Alias
  
Gene Name
 Tnnt2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
80EGPVEDTKPKPSRLFubiquitination[1]
82PVEDTKPKPSRLFMPubiquitination[1]
95MPNLVPPKIPDGERVubiquitination[1]
193EDEARKKKALSNMMHubiquitination[1]
207HFGGYIQKTERKSGKubiquitination[1]
231KILAERRKALAIDHLubiquitination[1]
246NEDQLREKAKELWQSubiquitination[1]
261IHNLEAEKFDLQEKFacetylation[2]
267EKFDLQEKFKQQKYEubiquitination[1]
269FDLQEKFKQQKYEINacetylation[2]
269FDLQEKFKQQKYEINubiquitination[1]
272QEKFKQQKYEINVLRacetylation[2]
272QEKFKQQKYEINVLRubiquitination[1]
287NRINDNQKVSKTRGKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 302 AA 
Protein Sequence
MSDAEEVVEE YEEEQKEGME EEDWSEEEED EQEEAVEEEE AGGAEPEPEG EAETEEANVE 60
EVGPDEEAKD AEEGPVEDTK PKPSRLFMPN LVPPKIPDGE RVDFDDIHRK RVEKDLNELQ 120
TLIEAHFENR KKEEEELISL KDRIEKRRAE RAEQQRIRNE REKERQNRLA EERARREEEE 180
NRRKAEDEAR KKKALSNMMH FGGYIQKTER KSGKRQTERE KKKKILAERR KALAIDHLNE 240
DQLREKAKEL WQSIHNLEAE KFDLQEKFKQ QKYEINVLRN RINDNQKVSK TRGKAKVTGR 300
WK 302 
Gene Ontology
 GO:0005861; C:troponin complex; IDA:MGI.
 GO:0005200; F:structural constituent of cytoskeleton; IDA:MGI.
 GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IMP:MGI.
 GO:0006936; P:muscle contraction; IDA:MGI.
 GO:0008016; P:regulation of heart contraction; IMP:MGI.
 GO:0045214; P:sarcomere organization; IMP:MGI.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI. 
Interpro
 IPR001978; Troponin. 
Pfam
 PF00992; Troponin 
SMART
  
PROSITE
  
PRINTS