CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028845
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 FACT complex subunit SSRP1 
Protein Synonyms/Alias
  
Gene Name
 Ssrp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
84FRESEFEKLSDFFKTacetylation[1]
84FRESEFEKLSDFFKTubiquitination[2]
100YRLELMEKDLCVKGWubiquitination[2]
105MEKDLCVKGWNWGTVubiquitination[2]
233HGKTFDYKIPYTTVLacetylation[1, 3]
413IEREEYGKLFDFVNAacetylation[1]
542SSEAKKGKDPNAPKRacetylation[4]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 623 AA 
Protein Sequence
MAETLEFNDI FQEVKGSMND GRLRLSRQGI IFKNSKTGKV DNIQAGELTE GIWRRVALGH 60
GLKLLTKNGH VYKYDGFRES EFEKLSDFFK THYRLELMEK DLCVKGWNWG TVKFGGQLLS 120
FDIGDQPVFE IPLSNVSQCT TGKNEVTLEF HQNDDAEVSL MEVRFYVPPT QEDGVDPVEA 180
FAQNVLSKAD VIQATGDAIC IFRELQCLTP RGRYDIRIYP TFLHLHGKTF DYKIPYTTVL 240
RLFLLPHKDQ RQMFFVISLD PPIKQGQTRY HFLILLFSKD EDISLTLNMN EEEVEKRFEG 300
RLTKNMSGSL YEMVSRVMKA LVNRKITVPG NFQGHSGAQC ITCSYKASSG LLYPLERGFI 360
YVHKPPVHIR FDEISFVNFA RGTTTTRSFD FEIETKQGTQ YTFSSIEREE YGKLFDFVNA 420
KKLNIKNRGL KEGINPGYDD YADSDEDQHD AYLERMKEEG KIREENANDS SDDSGEETDE 480
SFNPGEEEED VAEEFDSNAS ASSSSNEGDS DREEKKREQL KRAKMAKDRK SRRKSSEAKK 540
GKDPNAPKRP MSAYMLWLNA SREKIKSDHP GISITDLSKK AGEIWKGMSK EKKEEWDRKA 600
EDARREYEKA MKEYEGGRGD SSK 623 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR013719; DUF1747.
 IPR009071; HMG_box_dom.
 IPR011993; PH_like_dom.
 IPR000969; SSrcognition.
 IPR024954; SSRP1_dom. 
Pfam
 PF00505; HMG_box
 PF08512; Rtt106
 PF03531; SSrecog 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS
 PR00887; SSRCOGNITION.