| Tag | Content |
|---|
| CPLM ID | CPLM-013598 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | V-type proton ATPase subunit C 1 |
Protein Synonyms/Alias | V-ATPase subunit C 1; Vacuolar proton pump subunit C 1 |
Gene Name | Atp6v1c1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 37 | NNLAVSSKFNIPDLK | acetylation | [1] | | 119 | YPIKQSLKNISEIIA | acetylation | [1] | | 127 | NISEIIAKGVTQIDN | acetylation | [1] | | 137 | TQIDNDLKSRASAYN | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). |
Sequence Annotation | MOD_RES 2 2 N-acetylthreonine (By similarity). |
Keyword | Acetylation; Complete proteome; Hydrogen ion transport; Ion transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 382 AA |
Protein Sequence | MTEFWLISAP GEKTCQQTWE KLHAATTKNN NLAVSSKFNI PDLKVGTLDV LVGLSDELAK 60
LDAFVEGVVK KVAQYMADVL EDSKDKVQEN LLASGVDLVT YITRFQWDMA KYPIKQSLKN 120
ISEIIAKGVT QIDNDLKSRA SAYNNLKGNL QNLERKNAGS LLTRSLAEIV KKDDFVLDSE 180
YLVTLLVVVP KLNHNDWIKQ YETLAEMVVP RSSNVLSEDQ DSYLCNVTLF KKAVDDFRHK 240
ARENKFIVRD FQYNEEEMRA DKEEMNRLST DKKKQFGPLV RWLKVNFSEA FIAWIHIKAL 300
RVFVESVLRY GLPVNFQAML LQPNKKSVKK LREVLHELYK HLDSSAAAII DAPMDIPGLN 360
LSQQEYYPYV YYKIDCNLLE FK 382 |
Gene Ontology | GO:0045177; C:apical part of cell; IDA:RGD. GO:0031410; C:cytoplasmic vesicle; IDA:RGD. GO:0005886; C:plasma membrane; ISS:UniProtKB. GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro. GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Compara. GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |