UniProt Accession

 DTD1_MOUSE; Q9DD18; A2ANA2; Q3TY44; Q9CRE8; Q9CYL0; Q9D013; Q9D1G4 

Genbank Protein ID

 AK003594; AK010822; AK011917; AK017565; AK158898; AL844516; AL808119; AL808119; AL844516; BC026537 

Genbank Nucleotide ID

 BAB22882.1; BAB27205.1; BAB27914.1; BAB30808.1; BAE34719.1; CAM22364.1; CAM22364.1; CAM26713.1; CAM26713.1; AAH26537.1 

Protein Name

 D-tyrosyl-tRNA(Tyr) deacylase 1 

Protein Synonyms/Alias

  

Gene Name

 Dtd1 

Gene Synonyms/Alias

 Hars2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
90	QCVLKGNKPDFHLAM	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential). 

Sequence Annotation

 ACT_SITE 81 81 Nucleophile (By similarity).
 MOD_RES 196 196 Phosphoserine.
 MOD_RES 197 197 Phosphoserine (By similarity).
 MOD_RES 205 205 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
 GO:0019478; P:D-amino acid catabolic process; IEA:InterPro. 

Interpro

 IPR023509; DTD-like_dom.
 IPR003732; DTyrtRNA_deacyls. 

Pfam

 PF02580; Tyr_Deacylase 

SMART

  

PROSITE

  

PRINTS