CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021297
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial folate transporter/carrier 
Protein Synonyms/Alias
 Solute carrier family 25 member 32 
Gene Name
 SLC25A32 
Gene Synonyms/Alias
 MFT; MFTC 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
280EGVGGFYKGIAPNLIubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Transports folate across the inner membranes of mitochondria. 
Sequence Annotation
 REPEAT 20 109 Solcar 1.
 REPEAT 118 209 Solcar 2.
 REPEAT 222 306 Solcar 3.  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 315 AA 
Protein Sequence
MTGQGQSASG SSAWSTVFRH VRYENLIAGV SGGVLSNLAL HPLDLVKIRF AVSDGLELRP 60
KYNGILHCLT TIWKLDGLRG LYQGVTPNIW GAGLSWGLYF FFYNAIKSYK TEGRAERLEA 120
TEYLVSAAEA GAMTLCITNP LWVTKTRLML QYDAVVNSPH RQYKGMFDTL VKIYKYEGVR 180
GLYKGFVPGL FGTSHGALQF MAYELLKLKY NQHINRLPEA QLSTVEYISV AALSKIFAVA 240
ATYPYQVVRA RLQDQHMFYS GVIDVITKTW RKEGVGGFYK GIAPNLIRVT PACCITFVVY 300
ENVSHFLLDL REKRK 315 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; NAS:UniProtKB.
 GO:0008517; F:folic acid transporter activity; NAS:UniProtKB.
 GO:0046655; P:folic acid metabolic process; TAS:Reactome.
 GO:0006839; P:mitochondrial transport; IEA:InterPro. 
Interpro
 IPR002030; Mit_uncoupling.
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS
 PR00784; MTUNCOUPLING.