CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029444
UniProt Accession
Genbank Protein ID
 U62317 
Genbank Nucleotide ID
  
Protein Name
 C-Jun-amino-terminal kinase-interacting protein 2 
Protein Synonyms/Alias
 Uncharacterized protein 
Gene Name
 MAPK8IP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
309PDLTFSKKFLNVFVNubiquitination[1]
402HAVPGPAKDLLGSKRubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 558 AA 
Protein Sequence
MISSISETEL ELSSDGGSSS SGRSSHLTNS IEEASSPASE PEPPREPPRR PAFLPVGPDD 60
TNSEYESGSE SEPDLSEDAD SPWLLSNLVS RMISEGSSPI RCPGQCLSPA PRPPGEPVSP 120
AGGAAQDSQD PEAAAGPGGV ELVDMETLCA PPPPAPAAPR PGPAQPGPCL FLSNPTRDTI 180
TPLWAAPGRA ARPGRACSAA CSEEEDEEDD EEEEDAEDSA GSPGGRGTGP SAPRDASLVY 240
DAVKYTLVVD EHTQLELVSL RRCAGLGHDS EEDSGGEASE EEAGAALLGG GQVSGDTSPD 300
SPDLTFSKKF LNVFVNSTSR SSSTESFGLF SCLVNGEERE QTHRAVFRFI PRHPDELELD 360
VDDPVLVEAE EDDFWFRGFN MRTGERGVFP AFYAHAVPGP AKDLLGSKRS PCWVERFDVQ 420
FLGSVEVPCH QGNGILCAAM QKIATARKLT VHLRPPASCD LEISLRGVKL SLSGGGPEFQ 480
RCSHFFQMKN ISFCGCHPRN SCYFGFITKH PLLSRFACHV FVSQESMRPV AQSVGRAFLE 540
YYQEHLAYAC PTEDIYLE 558 
Gene Ontology
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0014069; C:postsynaptic density; IEA:Compara.
 GO:0001662; P:behavioral fear response; IEA:Compara.
 GO:0048813; P:dendrite morphogenesis; IEA:Compara.
 GO:0007254; P:JNK cascade; IEA:Compara.
 GO:0007617; P:mating behavior; IEA:Compara.
 GO:0046958; P:nonassociative learning; IEA:Compara.
 GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IEA:Compara.
 GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Compara.
 GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IEA:Compara.
 GO:0051966; P:regulation of synaptic transmission, glutamatergic; IEA:Compara.
 GO:0035176; P:social behavior; IEA:Compara. 
Interpro
 IPR011993; PH_like_dom.
 IPR006020; PTyr_interaction_dom.
 IPR001452; SH3_domain. 
Pfam
 PF00640; PID
 PF00018; SH3_1 
SMART
 SM00462; PTB
 SM00326; SH3 
PROSITE
 PS01179; PID
 PS50002; SH3 
PRINTS