CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039806
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kelch-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 KLHL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
325IGGRDGLKTLNTVECubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kelch repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 555 AA 
Protein Sequence
MDFPGPHEKG LVLQELKVEP DNSSQATGEG CGHRLVLSSV SDYFAAMFTS DVCEAKQEEI 60
KMEGIDPNAL WDLVQFAYTG CLELKEDTIE NLLAAACLLQ LPQVVEVCCH FLMKLLHPSN 120
CLGIRAFADA QGCIELMKVA HSYTMENIME VIRNQEFLLL PAEELHKLLA SDDVNVPDEE 180
TIFHALMMWV KYDMQSRCND LSMLLAFIRL PLLPPQILAD LENHALFKND LECQKLILEA 240
MKYHLLPERR TLMQSPRTKP RKSTVGTLYA VGGMDNNKGA TTIEKYDLRT NLWIQAGMMN 300
GRRLQFGVAV IDDKLFVIGG RDGLKTLNTV ECYNPKTKTW TVLPPMSTHR HGLGVTVLEG 360
PIYAVGGHDG WSYLNTVERW DPQSQQWTFV ASMSIARSTV GVAALNGKLY SVGGRDGSSC 420
LSSMEYYDPH TNKWNMCAPM CKRRGGVGVA TCDGFLYAVG GHDAPASNHC SRLLDYVERY 480
DPKTDTWTMV APLSMPRDAV GVCLLGDRLY AVGGYDGQTY LNTMESYDPQ TNEWTQMASL 540
NIGRAGACVV VIKQP 555 
Gene Ontology
  
Interpro
 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR015916; Gal_Oxidase_b-propeller.
 IPR017096; Kelch-like_gigaxonin.
 IPR006652; Kelch_1. 
Pfam
 PF07707; BACK
 PF00651; BTB
 PF01344; Kelch_1 
SMART
 SM00875; BACK
 SM00225; BTB
 SM00612; Kelch 
PROSITE
 PS50097; BTB 
PRINTS