CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024977
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MHC class I antigen 
Protein Synonyms/Alias
  
Gene Name
 HLA-B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
67DRNTQIYKAQAQTDRubiquitination[1, 2]
267VQHEGLPKPLTLRW*ubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 273 AA 
Protein Sequence
SHSMRYFYTS VSRPGRGEPR FISVGYVDDT QFVRFDSDAA SPREEPRAPW IEQEGPEYWD 60
RNTQIYKAQA QTDRESLRNL RGYYNQSEAG SHTLQSMYGC DVGPDGRLLR GYDQSAYDGK 120
DYIALNEDLR SWTAADTAAQ ITQRKWEAAR EAEQRRAYLE GECVEWLRRY LENGKDKLER 180
ADPPKTHVTH HPISDHEATL RCWALGFYPA EITLTWQRDG EDQTQDTELV ETRPAGDRTF 240
QKWAAVVVPS GEEQRYTCHV QHEGLPKPLT LRW 273 
Gene Ontology
 GO:0042612; C:MHC class I protein complex; IEA:InterPro.
 GO:0019882; P:antigen processing and presentation; IEA:InterPro.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2. 
Pfam
 PF07654; C1-set
 PF00129; MHC_I 
SMART
 SM00407; IGc1 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS
 PR01638; MHCCLASSI.