CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031228
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mannose-P-dolichol utilization defect 1 protein 
Protein Synonyms/Alias
 cDNA FLJ57793, moderately similar to Mannose-P-dolichol utilization defect 1 protein 
Gene Name
 MPDU1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
10AEADGPLKRLLVPILubiquitination[1, 2, 3]
44CLKILLSKGLGLGIVubiquitination[4]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 186 AA 
Protein Sequence
MAAEADGPLK RLLVPILLPE KCYDQLFVQW DLLHVPCLKI LLSKGLGLGI VAGSLLVKLP 60
QVFKILGAKS AEGLSLQSVM LELVALTGTM VYSITNNFPF RCRFPRLLRP GPAGASLTSD 120
ALDCSHPAPG LQCACCGGGE ASPGSHQLPQ RAHRPALSHH SLPAVWGLPG PNLHFHSGVS 180
IPFSQL 186 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:HPA.
 GO:0005739; C:mitochondrion; IDA:HPA. 
Interpro
 IPR006603; CTNS.
 IPR016817; MannP-dilichol_defect-1. 
Pfam
  
SMART
 SM00679; CTNS 
PROSITE
  
PRINTS