UniProt Accession

 MTCH2_MOUSE; Q791V5; Q3TPS5; Q99LZ6; Q9D060; Q9D7Y2; Q9QZP3 

Genbank Protein ID

 AF176009; AK003100; AK008487; AK008712; AK011785; AK011874; AK075890; AK161441; AK164169; BC002152; BC038899; BC038916 

Genbank Nucleotide ID

 AAD52647.1; BAB22565.1; BAB25694.1; BAB25848.1; BAB27839.1; BAB27892.1; BAC36033.1; BAE36399.1; BAE37660.1; AAH02152.1; AAH38899.1; AAH38916.1 

Protein Name

 Mitochondrial carrier homolog 2 

Protein Synonyms/Alias

  

Gene Name

 Mtch2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
90	LGTVVHGKVLQYYQE	ubiquitination	[1]
100	QYYQESEKPEELGSV	acetylation	[2]
100	QYYQESEKPEELGSV	ubiquitination	[1]
111	LGSVTVQKEYSSSFD	ubiquitination	[1]
158	QFIGRESKYCGLCDS	acetylation	[3]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647] 

Functional Description

 The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity). 

Sequence Annotation

 REPEAT 2 98 Solcar 1.
 REPEAT 118 206 Solcar 2.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 158 158 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 303 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 

Pfam

 PF00153; Mito_carr 

SMART

  

PROSITE

 PS50920; SOLCAR 

PRINTS