UniProt Accession

 H0Y8F1_HUMAN; H0Y8F1 

Genbank Protein ID

 AL355385 

Genbank Nucleotide ID

  

Protein Name

 Inactive tyrosine-protein kinase 7 

Protein Synonyms/Alias

  

Gene Name

 PTK7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
344	RCWALSPKDRPSFSE	ubiquitination	[1]
364	GDSTVDSKP******	ubiquitination	[1, 2]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Immunoglobulin domain; Membrane; Receptor; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 365 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
 IPR008266; Tyr_kinase_AS.
 IPR020635; Tyr_kinase_cat_dom. 

Pfam

 PF07679; I-set
 PF07714; Pkinase_Tyr 

SMART

 SM00219; TyrKc 

PROSITE

 PS50835; IG_LIKE
 PS50011; PROTEIN_KINASE_DOM
 PS00109; PROTEIN_KINASE_TYR 

PRINTS

 PR00109; TYRKINASE.