UniProt Accession

 B4DWA0_HUMAN; B4DWA0 

Genbank Protein ID

 AK301434 

Genbank Nucleotide ID

 BAG62962.1 

Protein Name

 cDNA FLJ54188, moderately similar to High mobility group protein HMG-I/HMG-Y 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
7	*MSESSSKSSQPLAS	ubiquitination	[1]
31	RGRGRPRKQPPVSPG	ubiquitination	[2]
46	TALVGSQKEPSEVPT	ubiquitination	[2]
55	PSEVPTPKRPRGRPK	ubiquitination	[2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 328 AA 

Protein Sequence

Gene Ontology

 GO:0000785; C:chromatin; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR020478; AT_hook-like.
 IPR017956; AT_hook_DNA-bd_motif.
 IPR000116; HMGI/HMGY.
 IPR000637; HMGI/Y_DNA-bd_CS. 

Pfam

  

SMART

 SM00384; AT_hook 

PROSITE

 PS00354; HMGI_Y 

PRINTS

 PR00929; ATHOOK.
 PR00930; HIGHMOBLTYIY.