CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Haptoglobin 
Protein Synonyms/Alias
 Haptoglobin, isoform CRA_a 
Gene Name
 Hp 
Gene Synonyms/Alias
 mCG_10187 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
111IGGSMDAKGSFPWQAubiquitination[1]
119GSFPWQAKMISRHGLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Disulfide bond. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 347 AA 
Protein Sequence
MRALGAVVTL LLWGQLFAVE LGNDAMDFED DSCPKPPEIA NGYVEHLVRY RCRQFYRLRA 60
EGDGVYTLND EKQWVNTVAG EKLPECEAVC GKPKHPVDQV QRIIGGSMDA KGSFPWQAKM 120
ISRHGLTTGA TLISDQWLLT TAKNLFLNHS ETASAKDITP TLTLYVGKNQ LVEIEKVVLH 180
PNHSVVDIGL IKLKQRVLVT ERVMPICLPS KDYIAPGRVG YVSGWGRNAN FRFTDRLKYV 240
MLPVADQDKC VVHYENSTVP EKKNLTSPVG VQPILNEHTF CAGLTKYQED TCYGDAGSAF 300
AIHDMEEDTW YAAGILSFDK SCAVAEYGVY VRATDLKDWV QETMAKN 347 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
 GO:0002526; P:acute inflammatory response; IEA:Compara.
 GO:0001889; P:liver development; IEA:Compara.
 GO:0031100; P:organ regeneration; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:InterPro.
 GO:0033590; P:response to cobalamin; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0051384; P:response to glucocorticoid stimulus; IEA:Compara.
 GO:0009408; P:response to heat; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0033591; P:response to L-ascorbic acid; IEA:Compara.
 GO:0010288; P:response to lead ion; IEA:Compara.
 GO:0032496; P:response to lipopolysaccharide; IEA:Compara.
 GO:0032026; P:response to magnesium ion; IEA:Compara.
 GO:0010165; P:response to X-ray; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara. 
Interpro
 IPR008292; Haptoglobin.
 IPR001254; Peptidase_S1.
 IPR001314; Peptidase_S1A.
 IPR000436; Sushi_SCR_CCP.
 IPR009003; Trypsin-like_Pept_dom. 
Pfam
 PF00089; Trypsin 
SMART
 SM00032; CCP
 SM00020; Tryp_SPc 
PROSITE
 PS50923; SUSHI
 PS50240; TRYPSIN_DOM 
PRINTS
 PR00722; CHYMOTRYPSIN.