CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003003
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein RecA 
Protein Synonyms/Alias
 Recombinase A 
Gene Name
 recA 
Gene Synonyms/Alias
 lexB; recH; rnmB; tif; umuB; zab; b2699; JW2669 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
287VKEKLIEKAGAWYSYacetylation[1]
Reference
 [1] The diversity of lysine-acetylated proteins in Escherichia coli.
 Yu BJ, Kim JA, Moon JH, Ryu SE, Pan JG.
 J Microbiol Biotechnol. 2008 Sep;18(9):1529-36. [PMID: 18852508] 
Functional Description
 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. 
Sequence Annotation
 NP_BIND 67 74 ATP.  
Keyword
 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; Reference proteome; SOS response; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 353 AA 
Protein Sequence
MAIDENKQKA LAAALGQIEK QFGKGSIMRL GEDRSMDVET ISTGSLSLDI ALGAGGLPMG 60
RIVEIYGPES SGKTTLTLQV IAAAQREGKT CAFIDAEHAL DPIYARKLGV DIDNLLCSQP 120
DTGEQALEIC DALARSGAVD VIVVDSVAAL TPKAEIEGEI GDSHMGLAAR MMSQAMRKLA 180
GNLKQSNTLL IFINQIRMKI GVMFGNPETT TGGNALKFYA SVRLDIRRIG AVKEGENVVG 240
SETRVKVVKN KIAAPFKQAE FQILYGEGIN FYGELVDLGV KEKLIEKAGA WYSYKGEKIG 300
QGKANATAWL KDNPETAKEI EKKVRELLLS NPNSTPDFSV DDSEGVAETN EDF 353 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0003684; F:damaged DNA binding; IEA:HAMAP.
 GO:0008094; F:DNA-dependent ATPase activity; IEA:HAMAP.
 GO:0003697; F:single-stranded DNA binding; IDA:EcoliWiki.
 GO:0048870; P:cell motility; IMP:EcoliWiki.
 GO:0006310; P:DNA recombination; IEA:HAMAP.
 GO:0006281; P:DNA repair; IEA:HAMAP.
 GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki.
 GO:0009432; P:SOS response; IMP:EcoliWiki. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR013765; DNA_recomb/repair_RecA.
 IPR020584; DNA_recomb/repair_RecA_CS.
 IPR020588; DNA_recomb_RecA/RadB_ATP-bd.
 IPR027417; P-loop_NTPase.
 IPR023400; RecA_C.
 IPR020587; RecA_monomer-monomer_interface. 
Pfam
 PF00154; RecA 
SMART
 SM00382; AAA 
PROSITE
 PS00321; RECA_1
 PS50162; RECA_2
 PS50163; RECA_3 
PRINTS
 PR00142; RECA.