CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Palmitoyl-protein thioesterase 
Protein Synonyms/Alias
  
Gene Name
 Ppt1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
175LNAGAYSKLVQERLVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 307 AA 
Protein Sequence
MMASSCSRRL LAAALLPWCC AAWALGHLDP PSPPPLVIWH GMGDSCCNPM SMGVIKKMVE 60
KEIPGIYVLS LEIGKNMMED VENSFFLNVN VQVNMVCQIL EKDPKLQQGY NAIGFSQGGQ 120
FLRAVAQRCP TPPMMTLISV GGQHQGVFGL PRCPGESSHI CDFIRKSLNA GAYSKLVQER 180
LVQAQYWHDP IKESVYRNYS IFLADINQER CVNESYKKNL MALKKFVMVK FFNDSIVDPV 240
DSEWFGFYRS GQAKETIPLQ ESTLYTEDRL GLKKMDKAGK LVFLAKEGDH LQISKEWFTA 300
HIIPFLK 307 
Gene Ontology
 GO:0030424; C:axon; IDA:MGI.
 GO:0030425; C:dendrite; IDA:MGI.
 GO:0005615; C:extracellular space; IDA:MGI.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005764; C:lysosome; IDA:MGI.
 GO:0045121; C:membrane raft; IEA:Compara.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0008021; C:synaptic vesicle; IEA:Compara.
 GO:0008474; F:palmitoyl-(protein) hydrolase activity; IDA:MGI.
 GO:0008344; P:adult locomotory behavior; IMP:MGI.
 GO:0006309; P:apoptotic DNA fragmentation; IEA:Compara.
 GO:0008306; P:associative learning; IMP:MGI.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0044257; P:cellular protein catabolic process; IMP:MGI.
 GO:0051186; P:cofactor metabolic process; IEA:Compara.
 GO:0051181; P:cofactor transport; IEA:Compara.
 GO:0007625; P:grooming behavior; IMP:MGI.
 GO:0016042; P:lipid catabolic process; IEA:Compara.
 GO:0007042; P:lysosomal lumen acidification; IEA:Compara.
 GO:0007040; P:lysosome organization; IMP:MGI.
 GO:0031579; P:membrane raft organization; IEA:Compara.
 GO:0030308; P:negative regulation of cell growth; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0007269; P:neurotransmitter secretion; IMP:MGI.
 GO:0006907; P:pinocytosis; IEA:Compara.
 GO:0048549; P:positive regulation of pinocytosis; IEA:Compara.
 GO:0048260; P:positive regulation of receptor-mediated endocytosis; IEA:Compara.
 GO:0002084; P:protein depalmitoylation; IMP:MGI.
 GO:0015031; P:protein transport; IEA:Compara.
 GO:0006898; P:receptor-mediated endocytosis; IEA:Compara.
 GO:0032429; P:regulation of phospholipase A2 activity; IMP:MGI.
 GO:0007601; P:visual perception; IMP:MGI. 
Interpro
 IPR002472; Palm_thioest. 
Pfam
 PF02089; Palm_thioest 
SMART
  
PROSITE
  
PRINTS
 PR00414; PPTHIESTRASE.