CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038841
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Dsp 
Protein Synonyms/Alias
  
Gene Name
 Dsp 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
879DRWQKIDKQIDFRLWacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2877 AA 
Protein Sequence
MSCNGGSHPR INTLGRMTRA ESGPDLRYEM TYSGGGGGGG GGGGGTSRMY YSRRCTVNDQ 60
NSDGYCQTGT MSRHQNQNTI QELLQNCADC LMRAELIAQP ELKFGEGIQL AWNRELDEYF 120
TQANDQMEII DGLIREMRQM GQPCDAYQKR LLQLQEQMRA LYKAISAPRV RRASSKGGYT 180
CQSGSGWDEF TKRLTGECLG WMRQQRAEMD LMAWGVDSGS VEQHINSHRS IHNAIGDYRW 240
QLDKIKADLR EKSAIYQLEE EYENLLKASF ERMDHLRQLQ NIIQATSREI MWINDCEEEE 300
LLYDWSDKNT NIAQKQEAFS IRMSQLEVKE KELNKLKQES DQLVLNQHPA SDKIEAYMDT 360
LQTQWSWILQ ITKCIDVHLK ENAAYFQFFE EAQSTEAYLK GLQDSIRKKY PCDKNMPLQH 420
LLEQIKELEK EREKILEYKR QVQNLVNKSK KIVQLKPRNP DYRSNKPIIL RALCDYKQDQ 480
KIVHKGDECI LKDNNERSKW YVTGPGGVDM LVPSVGLIIP PPNPLAVDLS CKIEQYYEAI 540
LALWNQLYIN MKSLVSWHYC MIDIEKIRAM TIAKLKTMRQ EDYMKTIEDL ELHYQDFIKN 600
SQGSEMFGDD DKRRMQSQFT DAQKHYQTLV IQLPGHPQHQ TVTKTEITHV GTCQDVNHNK 660
VIETNRENDK QETWLLMELQ KIRRQMEHCE ARMTLKNLLL TDQGSTHNIT VKINELKSVQ 720
NDSQALAEVL NQLKDMLANF RGSEKYCYLQ NEIFGLFQKL ENINGVTDGY LNSLCSVRAL 780
LQAILQTEDM LKVYEARLTE EETVCLDLDK VEAYRCGLKK IKNDLNLKKS LLATMKTELQ 840
KAQQIHSQSS QQYPLYDLDL GKFTEKVTQL TDRWQKIDKQ IDFRLWDLEK QIKQLRNYRD 900
NYQSFCKWLY DAKRRQDSLE SMKFGDSNTV MRFLNEQKNL HNEISGKRDK SEEVHKIAEL 960
CANSIKDYEL QLASYTSGLE TLLNIPIKRT MVQSPSGVIL QEAADIHARY IELLTRSGDY 1020
YRFLSEMLKS LEDLKLKNTK IEVLEEELRL ARDANSENCN KNKFLDQNLQ KYQAECSQFK 1080
AKLVSLEELK RQAELDGKSA KQNLDKCYGQ IKELNEKITR LTYEIEDEKR RRKTVEDRFD 1140
QQKNDYDQLQ KARQCEKESL GWQKLESEKA IKEKEYEIER LRVLLQEEGA RKREYENELA 1200
KVRNHYNEEM SNLRNKYETE INITKTTIKE ISMQKEDDSK NLRNQLDRLS RENRDLKDEI 1260
VRLNDSILQA TEQRRRAEEN ALQQKACGSE IMQKKQHLEV ELKQVIQQRS EDNARHKQSL 1320
EEAAKTIQDK NKEIERLKAE YQEEAKRRWE YENELSKVRN SYDEEIISLR NKFETEINIT 1380
KTTIHQLTMQ KEEDTSGYRA QIDNLTRENR SLSEEVKRLK NTLAQTTENL RRVEENVQQQ 1440
KASGSEMSQR KQQLEIELRQ VSQMRTEESM RYKQSLDDAA KTIQDKNKEI ERLKQLVDKE 1500
TNERKCLEDE NSKLQRVQYD LQKANNSATE AMSKLKVQEQ ELTRLRIDYE RVSQERTVKD 1560
QDITRIQSSL KDLQLQKQKA EEELSRLKRT ASDESSKRKM LEEELEAMRR SLKEQAVKIT 1620
NLTQQLEQAS IVKKRSEDDL RQQRDVLDGH VREKQRTQEE LRRLSLDVEA LRRQLVQEQE 1680
NVKQAHLRNE HFQKAIEDKS RSLNESKIEI ERLQSLTENL TKEHLMLEEE LRNLRLEYDD 1740
LRRGRSEADN DKNSTISELR SQLQISNNRT LELQGLINDL QRERENLRQE IEKFQKQALE 1800
ASNRIQESKS QCTQVVQERE SLLVKIKVLE QDKARLQRLE DELNRAKATL EAETRVKQRL 1860
ECEKQQIQND LNQWKTQYSR KEETIRKIES EREKSEREKN SLRSEIERLQ AEIKRIEERC 1920
RRKLEDSTRE TQSQLETERC RLQKEIDKLR QRPYGSHRET QTEYEWTVDS SKLVFDGLRK 1980
KVTAMQLYEC QLIDKTTLDK LLKGKKSVEE VASEIQPFLR GAGAIAGASA SPKEKYSLVE 2040
AKRKKFITPE STVMLLEAQA ATGGIIDPHR NEKLTVDNAI ARDLIDFDDR QQIYTAEKAI 2100
TGFDDPFSGK TVSVSEAIKK NLIDRETGMR LLEAQLASGG VVDPVNSVFL PKDVALARGL 2160
IDRDLYRSLN DPRDSQKNFV DPITKKKVSY MQLRERCRIE PHTGLLLLSV QKRSMSFQGI 2220
RQPVTVTELV DSGILRPSTV NELESGQISY DEVGERIKDF LQGSSCIAGI YNETTKQKLG 2280
IYEAMKIGLV RPGTALELLE AQAATGFIVD PVSNLRLPVE EAYKRGLVGI EFKEKLLSAE 2340
RAVTGYNDPE TGNIISLFQA MNKELIEKGH GIRLLEAQIA TGGIIDPKES HRLPVDMAYK 2400
RGYFNEELSE ILSDPSDDTK GFFDPNTEEN LTYLQLKERC IKDEETGLCL LPLKEKKKQV 2460
QTSQKNTLRK RRVVIVDPET NKEMSVQEAY KKGLIDYETF KELCEQECEW EEITITGSDG 2520
STRVVLVDRK TGSQYDIQDA IDKGLVDRKF FDQYRSGSLS LTQFADMISL KNGVGTSSGL 2580
SGSVNDDVFS SSRHESVSKI STISSVRNLT IRSSSLSDPL EESSPIAAIF DTENLEKISI 2640
TEGIERGIVD SITGQRLLEA QACTGGIIHP TTGQKLSLQD AVSQGLIDQD MATRLKPAQK 2700
AFIGFEGVKG KKKMSAAEAV KEKWLPYEAG QRFLEFQFLT GGLVDPEVHG RISTEEAIRK 2760
GFIDGRAAQR LQDISSYAKI LTCPKTKLKI SYKDAMNRSM VEDITGLRLL EAASVSSKGL 2820
PSPYNMSAPG SRSGSRSGSR SGSRSGSRSG SRRGSFDATG NSSYSYSYSF SSSSIGY 2877 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IEA:Compara.
 GO:0001533; C:cornified envelope; IEA:Compara.
 GO:0030057; C:desmosome; IDA:RGD.
 GO:0005916; C:fascia adherens; IDA:RGD.
 GO:0005882; C:intermediate filament; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:Compara.
 GO:0034332; P:adherens junction organization; IEA:Compara.
 GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IEA:Compara.
 GO:0016337; P:cell-cell adhesion; IEA:Compara.
 GO:0002934; P:desmosome organization; IEA:Compara.
 GO:0045109; P:intermediate filament organization; IEA:Compara.
 GO:0030216; P:keratinocyte differentiation; IEA:Compara.
 GO:0018149; P:peptide cross-linking; IEA:Compara.
 GO:0071896; P:protein localization to adherens junction; IEA:Compara.
 GO:0086091; P:regulation of heart rate by cardiac conduction; IEA:Compara.
 GO:0086005; P:regulation of ventricular cardiac muscle cell action potential; IEA:Compara.
 GO:0043588; P:skin development; IEA:Compara.
 GO:0003223; P:ventricular compact myocardium morphogenesis; IEA:Compara.
 GO:0042060; P:wound healing; IEP:RGD. 
Interpro
 IPR001101; Plectin_repeat.
 IPR018159; Spectrin/alpha-actinin. 
Pfam
 PF00681; Plectin 
SMART
 SM00250; PLEC
 SM00150; SPEC 
PROSITE
  
PRINTS