UniProt Accession

 J3QQL2_HUMAN; J3QQL2 

Genbank Protein ID

 AC087749 

Genbank Nucleotide ID

  

Protein Name

 Integrin beta 

Protein Synonyms/Alias

  

Gene Name

 ITGB4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
35	DYTIGFGKFVDKVSV	ubiquitination	[1, 2]
39	GFGKFVDKVSVPQTD	ubiquitination	[1, 2]
53	DMRPEKLKEPWPNSD	ubiquitination	[1, 2]
66	SDPPFSFKNVISLTE	ubiquitination	[2]
81	DVDEFRNKLQGERIS	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Cell adhesion; Complete proteome; Integrin; Membrane; Reference proteome; Transmembrane. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 114 AA 

Protein Sequence

Gene Ontology

 GO:0008305; C:integrin complex; IEA:InterPro.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0048870; P:cell motility; IEA:InterPro.
 GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
 GO:0031581; P:hemidesmosome assembly; IEA:InterPro.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW. 

Interpro

 IPR015812; Integrin_bsu.
 IPR012013; Integrin_bsu-4.
 IPR002369; Integrin_bsu_N.
 IPR002035; VWF_A. 

Pfam

 PF00362; Integrin_beta 

SMART

 SM00187; INB 

PROSITE

  

PRINTS

 PR01186; INTEGRINB.