CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037402
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 General transcription factor IIE subunit 1 
Protein Synonyms/Alias
  
Gene Name
 GTF2E1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
67RSVLNNLKGDKFIKCacetylation[1, 2]
104RTLVNVVKYKLDHMRubiquitination[3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 122 AA 
Protein Sequence
MADPDVLTEV PAALKRLAKY VIRGFYGIEH ALALDILIRN SCVKEEDMLE LLKFDRKQLR 60
SVLNNLKGDK FIKCRMRVET AADGKTTRHN YYFINYRTLV NVVKYKLDHM RRRIETDERD 120
ST 122 
Gene Ontology
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. 
Interpro
 IPR017919; TFIIE/TFIIEa_HTH.
 IPR024550; TFIIEa/SarR/Rpc3_HTH_dom. 
Pfam
 PF02002; TFIIE_alpha 
SMART
  
PROSITE
 PS51344; HTH_TFE_IIE 
PRINTS