CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015851
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sarcalumenin 
Protein Synonyms/Alias
  
Gene Name
 Srl 
Gene Synonyms/Alias
 Sar 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
64ADAAPGDKNLLLHYPubiquitination[1]
477RDRSHIDKTLMLNEDubiquitination[1]
485TLMLNEDKPADDYSAubiquitination[1]
506KIYHTSIKPLEQSYKubiquitination[1]
601RSFSPLEKFGQNFLEubiquitination[1]
609FGQNFLEKLIGIEVPacetylation[2]
618IGIEVPHKLLERVTFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 
Functional Description
 May be involved in the regulation of calcium transport. 
Sequence Annotation
 REGION 21 459 Acidic domain, probably binds calcium (By
 MOD_RES 229 229 Phosphothreonine.
 MOD_RES 304 304 Phosphoserine.
 MOD_RES 442 442 Phosphoserine.
 CARBOHYD 103 103 N-linked (GlcNAc...) (Potential).
 CARBOHYD 718 718 N-linked (GlcNAc...) (Potential).
 CARBOHYD 826 826 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Calcium; Complete proteome; Glycoprotein; Phosphoprotein; Reference proteome; Sarcoplasmic reticulum; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 910 AA 
Protein Sequence
MKALLLLCCF LASLLLSGQA ELQVSASGGT EDVGNLLENH FSAGDASLEE KERALYADAA 60
PGDKNLLLHY PDGREAESLE QTPAGAPSTA NGQGSETEAS LSNTSAAESA PPGDVEGPGE 120
EEEGPHAAGT LPPGGIEGPE EERPQFSSGK EPGQEEAGVG VPTEGAASME AEVQEGSSGV 180
PEELQGLLGD GPMNEAAGTA ESVVTQSSPP IEGKEAEGEG NTGSDHQSTE LDGTQDAIPA 240
GDESEAREGA EDKPQDYSLQ SEDTATPGPD HQPTDLHAAS DTASSGVEAE EGAEESKAEV 300
DTESGEKVED QGEPRPSLDA GSAIEANKQS EYTQARETEN DSPEGQVSGM SEEGLAEASS 360
EEEGGEEDGS ENGEVPFKEE SGEDSGDGAS SEEEGSTPGE AGEPQKTPGA TGHEEEGPQL 420
DVEDLNTGFE GSKTQDIEAE ASEERQQERG NPVIAQWEEV EDASEEAPLR DRSHIDKTLM 480
LNEDKPADDY SAVLQRLRKI YHTSIKPLEQ SYKYNELRQH EITDGEITSK PMVLFLGPWS 540
VGKSTMINYL LGLEDTRYQL YTGAEPTTSE FTVLMHGPKL KTIEGIVMAA DSARSFSPLE 600
KFGQNFLEKL IGIEVPHKLL ERVTFVDTPG IIENRKQQER GYPFNDVCQW FIDRADLIFV 660
VFDPTKLDVG LELEMLFRQL KGRESQIRII LNKADNLATQ MLMRVYGALF WSLAPLINVT 720
EPPRVYVSSF WPQDYKPDTH RELFLKEEIS LLEDLNQVIE NRLENKIAFI RQHAIRVRIH 780
ALLVDRYLQT YKDKMTFFSD GELVFKDIVE DPDKFYIFKT ILAKTNVSKF DLPNREAYKD 840
FFGINPISNF KLLSQQCSYM GGCFLEKIER AITQELPSLL GSIGLGKNPG APNCDKTGCG 900
ETPKNRYKKH 910 
Gene Ontology
 GO:0033018; C:sarcoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR001401; Dynamin_GTPase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00350; Dynamin_N 
SMART
  
PROSITE
  
PRINTS