| Tag | Content |
|---|
| CPLM ID | CPLM-011843 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-splicing factor PRP46 |
Protein Synonyms/Alias | Complexed with CEF1 protein 1; PRP nineteen-associated complex protein 50; PRP19-associated complex protein 50; Pre-mRNA-processing protein 46 |
Gene Name | PRP46 |
Gene Synonyms/Alias | CWC1; NTC50; YPL151C; P2594 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 7 | *MDGNDHKVENLGDV | acetylation | [1] | | 16 | ENLGDVDKFYSRIRW | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Involved in pre-mRNA splicing. May also be required for cell cycle progression at G2/M (By similarity). |
Sequence Annotation | REPEAT 137 168 WD 1.
REPEAT 180 210 WD 2.
REPEAT 222 252 WD 3.
REPEAT 264 294 WD 4.
REPEAT 306 335 WD 5.
REPEAT 348 377 WD 6.
REPEAT 397 427 WD 7. |
Keyword | Cell cycle; Complete proteome; Cytoplasm; Direct protein sequencing; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Repeat; Spliceosome; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 451 AA |
Protein Sequence | MDGNDHKVEN LGDVDKFYSR IRWNNQFSYM ATLPPHLQSE MEGQKSLLMR YDTYRKESSS 60
FSGEGKKVTL QHVPTDFSEA SQAVISKKDH DTHASAFVNK IFQPEVAEEL IVNRYEKLLS 120
QRPEWHAPWK LSRVINGHLG WVRCVAIDPV DNEWFITGSN DTTMKVWDLA TGKLKTTLAG 180
HVMTVRDVAV SDRHPYLFSV SEDKTVKCWD LEKNQIIRDY YGHLSGVRTV SIHPTLDLIA 240
TAGRDSVIKL WDMRTRIPVI TLVGHKGPIN QVQCTPVDPQ VVSSSTDATV RLWDVVAGKT 300
MKVLTHHKRS VRATALHPKE FSVASACTDD IRSWGLAEGS LLTNFESEKT GIINTLSINQ 360
DDVLFAGGDN GVLSFYDYKS GHKYQSLATR EMVGSLEGER SVLCSTFDKT GLRLITGEAD 420
KSIKIWKQDE TATKESEPGL AWNPNLSAKR F 451 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |