| Tag | Content |
|---|
| CPLM ID | CPLM-002888 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
Protein Synonyms/Alias | Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT |
Gene Name | murA |
Gene Synonyms/Alias | murZ; Rv1315; MT1355; MTCY149.01; MTCY373.35 |
Created Date | July 27, 2013 |
Organism | Mycobacterium tuberculosis |
NCBI Taxa ID | 1773 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 81 | ITAPDEPKYDADFAA | pupylation | [1] |
|
Reference | [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] . Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH. PLoS One. 2010 Jan 6;5(1):e8589. [ PMID: 20066036] |
Functional Description | Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity). |
Sequence Annotation | ACT_SITE 117 117 Proton donor (By similarity).
CROSSLNK 81 81 Isoglutamyl lysine isopeptide (Lys-Gln) |
Keyword | Cell cycle; Cell division; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Isopeptide bond; Peptidoglycan synthesis; Reference proteome; Transferase; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 418 AA |
Protein Sequence | MAERFVVTGG NRLSGEVAVG GAKNSVLKLM AATLLAEGTS TITNCPDILD VPLMAEVLRG 60
LGATVELDGD VARITAPDEP KYDADFAAVR QFRASVCVLG PLVGRCKRAR VALPGGDAIG 120
SRPLDMHQAG LRQLGAHCNI EHGCVVARAE TLRGAEIQLE FPSVGATENI LMAAVVAEGV 180
TTIHNAAREP DVVDLCTMLN QMGAQVEGAG SPTMTITGVP RLHPTEHRVI GDRIVAATWG 240
IAAAMTRGDI SVAGVDPAHL QLVLHKLHDA GATVTQTDAS FRVTQYERPK AVNVATLPFP 300
GFPTDLQPMA IALASIADGT SMITENVFEA RFRFVEEMIR LGADARTDGH HAVVRGLPQL 360
SSAPVWCSDI RAGAGLVLAG LVADGDTEVH DVFHIDRGYP LFVENLVSLG AEIERVCC 418 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0008760; F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity; IEA:HAMAP. GO:0007049; P:cell cycle; IEA:UniProtKB-KW. GO:0051301; P:cell division; IEA:UniProtKB-KW. GO:0040007; P:growth; IMP:MTBBASE. GO:0009252; P:peptidoglycan biosynthetic process; IEA:HAMAP. GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. GO:0019277; P:UDP-N-acetylgalactosamine biosynthetic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |