CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035636
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Zyx 
Protein Synonyms/Alias
  
Gene Name
 Zyx 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
24PAFYAPQKKFAPVVAacetylation[1]
25AFYAPQKKFAPVVAPacetylation[1]
33FAPVVAPKPKVNPFRacetylation[1]
270KFTPVASKFSPGAPSacetylation[1]
314TYAQQKEKPLVQEKQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 564 AA 
Protein Sequence
MAAPRPPPAI SVSVSAPAFY APQKKFAPVV APKPKVNPFR PGDSESPVAA GAQRAQMGRV 60
GEIPPPPPED FPLPPPPVIG EGDDSEGALG GAFPPPPPPL IEEPFPPAPL EEDIFPSPPP 120
PLEEEGGPEA PTQLPPQPRE KVSSIDLEID SLSSLLDDMT KNDPFKARVS SGYVPPPVAT 180
PFVPKPSTKP APVGTAPLPP WKAPSSSQPP PQPQAKPQVQ LHAQPQAKPH VQPQSVSSAN 240
TQPRGPLSQA PTPAPKFAPV APKFTPVASK FSPGAPSGPG PQPSQKSVPL EAPSSVGTGS 300
PQPPSFTYAQ QKEKPLVQEK QHPLPPPAQN QNQVRSPGGP GPLTLKEVEE LEQLTQQLMQ 360
DMEHPQRQSV AVNESCGKCS QPLARAQPAV RALGQLFHIT CFTCHQCQQQ LQGQQFYSLE 420
GAPYCEGCYT DTLEKCNTCG QPITDRMLRA TGKAYHPHCF TCVVCACPLE GTSFIVDQAN 480
QPHCVPDYHK QYAPRCSVCS EPIMPEPGRD ETVRVVALDK NFHMKCYKCE DCGKALSIEA 540
DDNGCFPLDG HVLCRKCHSA RAQT 564 
Gene Ontology
 GO:0005913; C:cell-cell adherens junction; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0001725; C:stress fiber; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0050727; P:regulation of inflammatory response; IEP:RGD. 
Interpro
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM 
SMART
 SM00132; LIM 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 
PRINTS