CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017985
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fibronectin type 3 and ankyrin repeat domains protein 1 
Protein Synonyms/Alias
  
Gene Name
 FANK1 
Gene Synonyms/Alias
 HSD13; UNQ6504/PRO21382 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19PHPPVVGKVTHHSIEacetylation[1]
33ELYWDLEKKAKRQGPacetylation[1]
34LYWDLEKKAKRQGPQacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 8 105 Fibronectin type-III.
 REPEAT 109 139 ANK 1.
 REPEAT 143 172 ANK 2.
 REPEAT 176 205 ANK 3.
 REPEAT 209 238 ANK 4.
 REPEAT 243 273 ANK 5.
 REPEAT 277 306 ANK 6.  
Keyword
 Alternative splicing; ANK repeat; Complete proteome; Cytoplasm; Nucleus; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 345 AA 
Protein Sequence
MEPQKIMPPS KPHPPVVGKV THHSIELYWD LEKKAKRQGP QEQWFRFSIE EEDPKMHTYG 60
IIYTGYATKH VVEGLEPRTL YRFRLKVTSP SGECEYSPLV SVSTTREPIS SEHLHRAVSV 120
NDEDLLVRIL QGGRVKVDVP NKFGFTALMV AAQKGYTRLV KILVSNGTDV NLKNGSGKDS 180
LMLACYAGHL DVVKYLRRHG ASWQARDLGG CTALHWAADG GHCSVIEWMI KDGCEVDVVD 240
TGSGWTPLMR VSAVSGNQRV ASLLIDAGAN VNVKDRNGKT PLMVAVLNNH EELVQLLLDK 300
GADASVKNEF GKGVLEMARV FDRQSVVSLL EERKKKQRPK KSCVC 345 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold. 
Pfam
 PF00023; Ank
 PF12796; Ank_2 
SMART
 SM00248; ANK
 SM00060; FN3 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50853; FN3 
PRINTS
 PR01415; ANKYRIN.