CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004671
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ty transcription activator TEC1 
Protein Synonyms/Alias
  
Gene Name
 TEC1 
Gene Synonyms/Alias
 ROC1; YBR083W; YBR0750 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
54VSTAACVKNEAEDNIsumoylation[1, 2]
Reference
 [1] Pheromone-regulated sumoylation of transcription factors that mediate the invasive to mating developmental switch in yeast.
 Wang Y, Dohlman HG.
 J Biol Chem. 2006 Jan 27;281(4):1964-9. [PMID: 16306045]
 [2] Sumoylation of transcription factor Tec1 regulates signaling of mitogen-activated protein kinase pathways in yeast.
 Wang Y, Abu Irqeba A, Ayalew M, Suntay K.
 PLoS One. 2009 Oct 14;4(10):e7456. [PMID: 19826484
Functional Description
 TEC1 is involved in the activation of TY1 and TY1- mediated gene expression. It is not involved in mating or sporulation processes. 
Sequence Annotation
 DNA_BIND 127 192 TEA.  
Keyword
 Activator; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 486 AA 
Protein Sequence
MSLKEDDFGK DNSRNIESYT GRIFDVYIQK DSYSQSALDD MFPEAVVSTA ACVKNEAEDN 60
INLIDTHPQF ELVNTGLGAK SDDLKSPSAK ATFTDKQRKN EVPNISVSNY FPGQSSETSS 120
TTESWTIGCD KWSEKVEEAF LEALRLIMKN GTTKIKIRNA NFGRNELISL YIKHKTNEFR 180
TKKQISSHIQ VWKKTIQNKI KDSLTLSSKE KELLHLIEHG AEQTTENSNL FYDIFEEIID 240
SLPSVSDSGS LTPKNLYVSN NSSGLSVHSK LLTPITASNE KKIENFIKTN AASQAKTPLI 300
YAKHIYENID GYKCVPSKRP LEQLSPTELH QGDRPNKASF SNKKAILESA KKIEIEQRKI 360
INKYQRISRI QEHESNPEFS SNSNSGSEYE SEEEVVPRSA TVTQLQSRPV PYYKNNGMPY 420
SLSKVRGRPM YPRPAEDAYN ANYIQGLPQY QTSYFSQLLL SSPQHYEHSP HQRNFTPSNQ 480
SHGNFY 486 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.
 GO:0001135; F:RNA polymerase II transcription factor recruiting transcription factor activity; IMP:SGD.
 GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
 GO:0001300; P:chronological cell aging; IMP:SGD.
 GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.
 GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IDA:SGD.
 GO:0010527; P:positive regulation of transposition, RNA-mediated; IMP:SGD.
 GO:0007124; P:pseudohyphal growth; IMP:SGD. 
Interpro
 IPR000818; TEA/ATTS. 
Pfam
 PF01285; TEA 
SMART
 SM00426; TEA 
PROSITE
 PS00554; TEA_1
 PS51088; TEA_2 
PRINTS
 PR00065; TEADOMAIN.