UniProt Accession

 THO1_YEAST; P40040; D3DLW8 

Genbank Protein ID

 U18813; AY557779; BK006939 

Genbank Nucleotide ID

 AAB64599.1; AAS56105.1; DAA07722.1 

Protein Name

 Protein THO1 

Protein Synonyms/Alias

  

Gene Name

 THO1 

Gene Synonyms/Alias

 YER063W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
142	KKLHRANKFGQDQAD	acetylation	[1]
142	KKLHRANKFGQDQAD	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Unknown; suppressor of the transcriptional defect of HPR1 by overexpression. 

Sequence Annotation

 DOMAIN 4 38 SAP.
 MOD_RES 22 22 Phosphoserine.
 MOD_RES 58 58 Phosphoserine.
 MOD_RES 68 68 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:SGD.
 GO:0003682; F:chromatin binding; IDA:SGD.
 GO:0003690; F:double-stranded DNA binding; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0016973; P:poly(A)+ mRNA export from nucleus; IGI:SGD.
 GO:0022618; P:ribonucleoprotein complex assembly; IMP:SGD.
 GO:0006351; P:transcription, DNA-dependent; IGI:SGD. 

Interpro

 IPR003034; SAP_dom. 

Pfam

 PF02037; SAP 

SMART

 SM00513; SAP 

PROSITE

 PS50800; SAP 

PRINTS